ChemicalBook Product Catalog Biochemical Engineering Inhibitors DNA damage ATM / ATR inhibitor VE 822

VE 822

VE 822 Basic information
Product Name:VE 822
Synonyms:VX970 (VE-822);2-Pyrazinamine, 3-[3-[4-[(methylamino)methyl]phenyl]-5-isoxazolyl]-5-[4-[(1-methylethyl)sulfonyl]phenyl]-;VX970;3-[3-[4-[(Methylamino)methyl]phenyl]-5-isoxazolyl]-5-[4-[(1-methylethyl)sulfonyl]phenyl]-2-pyrazinamine VE-822;VE 822 3-[3-[4-[(Methylamino)methyl]phenyl]-5-isoxazolyl]-5-[4-[(1-methylethyl)sulfonyl]phenyl]-2-pyrazinamine;VE 822;3-[3-[4-[(Methylamino)methyl]phenyl]-5-isoxazolyl]-5-[4-[(1-methylethyl)sulfonyl]phenyl]-2-pyrazinamine;VE822; VE 822
CAS:1232416-25-9
MF:C24H25N5O3S
MW:463.55
EINECS:1592732-453-0
Product Categories:Inhibitors
Mol File:1232416-25-9.mol
VE 822 Structure
VE 822 Chemical Properties
Melting point >197°C (dec.)
Boiling point 674.4±55.0 °C(Predicted)
density 1.263±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
pka8.88±0.10(Predicted)
form Solid
color Light Yellow
Safety Information
MSDS Information
VE 822 Usage And Synthesis
Uses3-[3-[4-[(Methylamino)methyl]phenyl]-5-isoxazolyl]-5-[4-[(1-methylethyl)sulfonyl]phenyl]-2-pyrazinamine is a novel ATR (ATM-Rad3-related) inhibitor for in vitro and in vivo radiosensatization.
DefinitionChEBI: 3-[3-[4-(methylaminomethyl)phenyl]-5-isoxazolyl]-5-(4-propan-2-ylsulfonylphenyl)-2-pyrazinamine is a sulfonamide.
VE 822 Preparation Products And Raw materials
Olaparib Pimodivir VX-770 Telaprevir KU-60019 VE-821 AVN-944 (S)-1-((S)-2-(4-amino-3-chlorobenzamido)-3,3-dimethylbutanoyl)-N-((2R,3S)-2-ethoxy-5-oxotetrahydrofuran-3-yl)pyrrolidine-2-carboxamide Y27632 (hydrochloride) VX-745 Bortezomib NU7441 (KU-57788)
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