Chemical Properties | white to beige crystalline powder or crystals |
Uses | Benzophenone estrogenicity toxicity structure activity. |
Uses | 4-Methylbenzophenone is used as clear coatings for wood, plastic and metal, overprint varnish. |
Uses | 4-Methylbenzophenone may be used as a reference standard for the determination of the analyte in breakfast cereals, paperboard food packaging and packed milk by various chromatography techniques. |
Synthesis Reference(s) | Journal of the American Chemical Society, 82, p. 1223, 1960 DOI: 10.1021/ja01490a047 Tetrahedron Letters, 40, p. 3109, 1999 DOI: 10.1016/S0040-4039(99)00476-1 Synthesis, p. 776, 1977 DOI: 10.1055/s-1977-24573 |
General Description | 4-Methylbenzophenone is a photo-initiator for printing inks, mainly applied to the cardboard boxes used for packing. It is reported to be a non-genotoxic carcinogen. However, it can contaminate foodstuffs when it comes in contact with the package contents. |
Flammability and Explosibility | Notclassified |
Safety Profile | Poison by
intraperitoneal route. A flammable liquid.
When heated to decomposition it emits
acrid smoke and irritating fumes. |
Purification Methods | Crystallise the ketone from MeOH, Et2O (m 58-59o) or pet ether. The cis-oxime has m 154o(153-156o) (from EtOH), and the trans-oxime has m 114-116o (from pet ether). [Beilstein 7 H 440, 7 III 2127, 7 IV 1403.] |