2,3-dimethyl-2H-indazol-6-amine hydrochloride

2,3-dimethyl-2H-indazol-6-amine hydrochloride Basic information

Product Name:	2,3-dimethyl-2H-indazol-6-amine hydrochloride
Synonyms:	2,3-dimethyl-2H-indazol-6-amine hydrochloride;2,3-Dimethyl-2H-indazol-6-amine monohydrochloride;2,3-Dimethyl-6-amino-2H-indazole hydrochloride;2H-Indazol-6-aMine,2,3-diMethyl-, hydrochloride (1:1);3-Methyl-6-nitro-1H-indazole hydrochloride;6-amino-2,3-dimethylindazole hydrochloride;Pazopanib Impurity 21;PAZ20
CAS:	635702-60-2
MF:	C9H12ClN3
MW:	197.66468
EINECS:	200-001-8
Product Categories:
Mol File:	635702-60-2.mol

2,3-dimethyl-2H-indazol-6-amine hydrochloride Chemical Properties

Melting point	>230°C (dec.)
storage temp.	Inert atmosphere,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
color	Pale Beige to Light Beige
Stability:	Hygroscopic

Safety Information

MSDS Information

2,3-dimethyl-2H-indazol-6-amine hydrochloride Usage And Synthesis

Uses	2,3-Dimethyl-6-amino-2H-indazole is an impurity in the synthesis of Pazopanib (P210925) hydrochloride, an oral angiogenesis inhibitor targeting VEGFR and PDGFR.

2,3-dimethyl-2H-indazol-6-amine hydrochloride Preparation Products And Raw materials

Raw materials	2,3-DIMETHYL-6-NITRO-2H-INDAZOLE-->3-Methyl-6-nitroindazole
Preparation Products	N-(4-chloro-2-pyrimidinyl)-N,2,3-trimethyl-2H-Indazol-6-amine-->N-(2-chloropyriMidin-4-yl)-2,3-diMethyl-2H- indazol-6-aMine

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