ChemicalBook Product Catalog Biochemical Engineering Saccharides Polysaccharide CITRATE SYNTHASE

CITRATE SYNTHASE

CITRATE SYNTHASE Basic information
Product Name:CITRATE SYNTHASE
Synonyms:EC 4.1.3.7;CITRATE CONDENSING ENZYME;CITRATE SYNTHASE;CITRATE OXALOACETATELYASE;CITRATE OXALOACETATE LYASE [COA-ACETYLATING;CS;citrate synthase from chicken heart;citrate synthase from porcine heart
CAS:9027-96-7
MF:C6H5O7-3
MW:189.0997
EINECS:232-821-7
Product Categories:Lyases;Specialty Enzymes
Mol File:9027-96-7.mol
CITRATE SYNTHASE Structure
CITRATE SYNTHASE Chemical Properties
storage temp. 2-8°C
solubility H2O: soluble1.0mg/mL, clear
form ammonium sulfate suspension
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
ToxicityA fine powder used in riot control because of its property of inducing acute irritation to the eyes, to any skin abrasion and to the tissues of the respiratory passages, causing coughing and nausea.
MSDS Information
ProviderLanguage
SigmaAldrich English
CITRATE SYNTHASE Usage And Synthesis
UsesCitrate Synthase from porcine heart has been used:
  • to inject newt egg for determining its importance in egg activation at fertilization
  • in the preparation of reaction mix to determine pyruvate carboxylase enzyme activity
  • to examine whether it can induce a [Ca2+]?increase and egg activation in unfertilized eggs

DefinitionAn enzyme that catalyzes the condensation of oxaloacetic acid and acetyl-CoA to yield citric acid and coenzyme A.
Biochem/physiol ActionsCitrate synthase catalyses the conversion of citrate to acetyl-CoA in the presence of coenzyme-A with the release of H2O and oxaloacetate. The enzyme has a molecular weight of 85 kDa and a pI of 6.1-6.6. It is inhibited by fluoroacetyl-CoA, palmitoyl-CoA, and citroyl-CoA. It is also inhibited when it is acetylated by acetic anhydride or iodinated by iodine.
CITRATE SYNTHASE Preparation Products And Raw materials
Raw materialsKAOLIN-->Trichloroacetic acid-->Pancreatin
Aluminum acetylacetonate METHYL ISOCYANOACETATE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) N-BUTYLISOCYANIDE PHENYLSELENOL Tris(2,4-pentanedionato)chroMiuM(III) DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) SALCOMINE 2,4-PENTANEDIONE, SILVER DERIVATIVE 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Tosylmethyl isocyanide COBALT(II) ACETYLACETONATE Cupric acetylacetonate Ethyl isocyanoacetate Ferric acetylacetonate COBALT ETHYLENE DIAMINE CHLORIDE Benzyl isocyanide TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III)
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