ChemicalBook Product Catalog Flavors and fragrances Synthetic fragrances Oxygen-containing heterocyclic compounds Thiazole, thiophene, and pyridine 3-MORPHOLINONE, 4-[4-[(5S)-5-(AMINOMETHYL)-2-OXO-3-OXAZOLIDINYL]PHENYL]-

3-MORPHOLINONE, 4-[4-[(5S)-5-(AMINOMETHYL)-2-OXO-3-OXAZOLIDINYL]PHENYL]-

3-MORPHOLINONE, 4-[4-[(5S)-5-(AMINOMETHYL)-2-OXO-3-OXAZOLIDINYL]PHENYL]- Basic information
Product Name:3-MORPHOLINONE, 4-[4-[(5S)-5-(AMINOMETHYL)-2-OXO-3-OXAZOLIDINYL]PHENYL]-
Synonyms:(S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one;Des(5-chloro-2-carboxythienyl) Rivaroxaban;Rivaroxaban Intermediate 3;4-{4-[(5S)-5-(aMinoMethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}Morpholin-3-one;4-{4-[(5S)-5-aminomethyl)-2-oxo-1,3-oxazolidin-3-yl}morpholin-3-on;4-[4-[(5S)-5-(AMinoMethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-Morpholinone;Rivaroxaban interMediate C;Rivaroxaban Aminomethyl Impurity
CAS:446292-10-0
MF:C14H17N3O4
MW:291.3
EINECS:692-970-2
Product Categories:Amines;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Aromatics;Intermediates
Mol File:446292-10-0.mol
3-MORPHOLINONE, 4-[4-[(5S)-5-(AMINOMETHYL)-2-OXO-3-OXAZOLIDINYL]PHENYL]- Structure
3-MORPHOLINONE, 4-[4-[(5S)-5-(AMINOMETHYL)-2-OXO-3-OXAZOLIDINYL]PHENYL]- Chemical Properties
Melting point 148.3-149.8 °C
Boiling point 580.4±45.0 °C(Predicted)
density 1.348±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka8.96±0.29(Predicted)
Safety Information
MSDS Information
3-MORPHOLINONE, 4-[4-[(5S)-5-(AMINOMETHYL)-2-OXO-3-OXAZOLIDINYL]PHENYL]- Usage And Synthesis
Chemical PropertiesWhite Solid
UsesA metabolite of Rivaroxaban (R538000).
UsesRivaroxaban intermediate.
3-MORPHOLINONE, 4-[4-[(5S)-5-(AMINOMETHYL)-2-OXO-3-OXAZOLIDINYL]PHENYL]- Preparation Products And Raw materials
Rivaroxaban iMpurity 8 (R)-5-chloro-N-(4-(3-oxomorpholino)phenyl)-N- ((2-oxooxazolidin-5-yl)methyl)thiophene-2-carboxamide 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- 2-ThiophenecarboxaMide, N-[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]- 3,5-dichlorothiophene-2-carboxylic acid Rivaroxaban Impurity 74 Rivaroxaban Impurity 55 Rivaroxaban Impurity 63 4-(4-AMINOPHENYL)MORPHOLIN-3-ONE Rivaroxaban iMpurity 6 Benzoic acid, 2-[[[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]aMino]carbonyl]- 3-Morpholinone, 4-(2,4-diaMinophenyl)- (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one.HCl 4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one (S)-(+)-GLYCIDYL PHTHALIMIDE 4-(4-NITROPHENYL)MORPHOLIN-3-ONE POLYSTYRENE IODOSOACETATE 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-
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