Dimethoxybenzene

Dimethoxybenzene Basic information
Product Name:Dimethoxybenzene
Synonyms:1,3-methoxybenzenel;1,3-Dimethoxybenzene, 97+%;3-DiMethoxybenzene;Benzene,1,3-dimethoxy-;Dimethylether resorcinolu;dimethyletherresorcinolu;Dimethylresorinol;m-dimethoxy-benzen
CAS:151-10-0
MF:C8H10O2
MW:138.16
EINECS:205-783-4
Product Categories:Benzene derivates;Aromatic Ethers
Mol File:151-10-0.mol
Dimethoxybenzene Structure
Dimethoxybenzene Chemical Properties
Melting point -52°C
Boiling point 85-87 °C7 mm Hg(lit.)
density 1.055 g/mL at 25 °C(lit.)
FEMA 2385 | M-DIMETHOXYBENZENE
refractive index n20/D 1.524(lit.)
Fp 190 °F
storage temp. Sealed in dry,Room Temperature
solubility Miscible with toluene.
form Liquid
color Clear colorless to slightly brown
Odorat 1.00 % in dipropylene glycol. acid fruity nutmeg neroli
Odor Typemedicinal
Water Solubility 1.216g/L(25 ºC)
JECFA Number1249
BRN 878582
LogP2.21
CAS DataBase Reference151-10-0(CAS DataBase Reference)
NIST Chemistry ReferenceBenzene, 1,3-dimethoxy-(151-10-0)
EPA Substance Registry Systemm-Dimethoxybenzene (151-10-0)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 24/25
RIDADR NA 1993 / PGIII
WGK Germany 2
RTECS CZ6474000
Hazard Note Irritant
TSCA Yes
HS Code 29093090
Toxicitymouse,LD50,intraperitoneal,900mg/kg (900mg/kg),BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)BEHAVIORAL: ATAXIABEHAVIORAL: TREMOR,Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 46, Pg. 185, 1957.
MSDS Information
ProviderLanguage
Resorcinol dimethyl ether English
SigmaAldrich English
ACROS English
ALFA English
Dimethoxybenzene Usage And Synthesis
Chemical Propertiesclear colorless to slightly brown liquid
Chemical Propertiesm-Dimethoxybenzene has a very powerful sweet-earthy, intensely, nut-like aroma.
OccurrenceReported found in Gruyere de Comte, blue cheeses, filberts and cognac
UsesOrganic intermediate, flavoring.
Uses1,3-Dimethoxybenzene is used for the preparation of oxathiane spiroketal donors. It is also used for the formation of pi- and O-ylidic complexes with dichlorocarbene. Further, it acts as a flavoring agent.
DefinitionChEBI: 1,3-Dimethoxybenzene is a member of methoxybenzenes.
PreparationFrom resorcinol by methylation using dimethyl sulfate and alka
Taste threshold valuesChemical, medicinal, spice, cooling root beer-like.
Synthesis Reference(s)The Journal of Organic Chemistry, 55, p. 991, 1990 DOI: 10.1021/jo00290a033
General Description1,3-Dimethoxybenzene can be used as a flavoring agent in the food industry. It is reported to be found in the volatiles of port wine and Roquefort cheese.
Purification MethodsExtract it with aqueous NaOH, and water, then dry it. Fractionally distil it from BaO or Na. [Beilstein 6 IV 5663.]
Dacthal O-Phthalimide N,N-Dimethylformamide Dimethyldimethoxysilane ETHANE 1,2-Dimethoxybenzene Resorcinol 2,3-Dimethoxybenzaldehyde 2,3-Dimethoxybenzoic acid Dimethyl fumarate 1,1-Dimethoxyethane Phthalates Dibutyl phthalate Dimethyl sulfoxide Dimethyl ether Dimethyl carbonate DME Dimethyl sulfate

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