N,2,3-Trimethyl-2-isopropylbutamide

N,2,3-Trimethyl-2-isopropylbutamide Basic information
Product Name:N,2,3-Trimethyl-2-isopropylbutamide
Synonyms:N,2,3-TRIMETHYL-2-ISOPROPYLBUTAMIDE;N,2,3-Trimethyl-2-(1-methylethyl)butanamide;Butanamide, N,2,3-trimethyl-2-(1-methylethyl);N-Methyl-2,2-diisopropylpropanamide;2-Isopropyl-N,2,3-trimethylbutyramide;Cooling Agent Ws23;2-Isoprop;COOLER 23(WS-23)
CAS:51115-67-4
MF:C10H21NO
MW:171.28
EINECS:256-974-4
Product Categories:
Mol File:51115-67-4.mol
N,2,3-Trimethyl-2-isopropylbutamide Structure
N,2,3-Trimethyl-2-isopropylbutamide Chemical Properties
Melting point 58-61 °C
Boiling point bp0.35mm 83-85°
density 0.9419 (rough estimate)
vapor pressure 0.3-0.32Pa at 25℃
FEMA 3804 | 2-ISOPROPYL-N,2,3-TRIMETHYLBUTYRAMIDE
refractive index 1.4621 (estimate)
storage temp. Sealed in dry,Room Temperature
pka16.46±0.46(Predicted)
form Solid
color White to Almost white
Odorat 25.00 % in dipropylene glycol. mild cooling mentholic minty
Odor Typeminty
JECFA Number1595
Merck 14,9716
LogP2.5 at 25℃ and pH7
CAS DataBase Reference51115-67-4(CAS DataBase Reference)
EPA Substance Registry SystemButanamide, N,2,3-trimethyl-2-(1-methylethyl)- (51115-67-4)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38-52/53
Safety Statements 37/39-26
HS Code 29242990
MSDS Information
ProviderLanguage
N,2,3-Trimethyl-2-(1-methylethyl)butanamide English
ACROS English
N,2,3-Trimethyl-2-isopropylbutamide Usage And Synthesis
Chemical Properties2-Isopropyl-N-2,3-trimethylbutyramide has a cool, mint–menthol-type odor
Chemical PropertiesN,2,3-Trimethyl-2-isopropylbutanamide is a white, crystalline powder,which gives a physiological cooling sensation on skin or mucosa. It is mainly used to create cooling and freshness in oral care preparations.
The material can be prepared by a Ritter reaction using N,2,3-trimethyl-2- isopropylbutyronitrile as the starting material and alkylating agents such as, for example, borates, carbonates, or phosphates.
UsesPhysiological coolant in foods, beverages, tobacco products, toiletries, cosmetics and pharmaceuticals.
Uses2-Isopropyl-N,2,3-trimethylbutanamide is flavored compound and comprising the recount flavored compound for electronic cigarette liquid.
DefinitionChEBI: N,2,3-Trimethyl-2-(1-methylethyl)butanamide is a fatty amide.
Aroma threshold valuesAroma characteristics at 5.0%: slight cooling impact with little character.
Taste threshold valuesTaste characteristics at 20 ppm: high-impacting cooling that lasts on the tongue and palate.
Trade nameWinsense WS-23 (Renessenz).
N,2,3-Trimethyl-2-isopropylbutamide Preparation Products And Raw materials
4-Methoxybenzyl alcohol Chloromethyl isopropyl carbonate CBI-BB ZERO/004639 RARECHEM AQ TC 1047 Trimethyl borate neosurugatoxin CHEMBRDG-BB 7805224 3-Methyl-2-butanone N,N-Dimethylformamide 2-Butanone Lauramidopropyl betaine 18-dehydroxycytochalasin H DI-SEC-BUTYL-BUTABARBITAL CBI-BB ZERO/004818 N,N'-Methylenebisacrylamide Butyramide N,N-Dimethylacetamide Cocoyl amide propyldimethyl glycine

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