Bucladesine

Bucladesine Basic information
Product Name:Bucladesine
Synonyms:BUCLADESINE;Dibutyryladenosine cyclic 3',5'-monophosphate;Calciuml Dibutyryladenosine Cyclophosphate;n-6,o-2'-dibutyryl adenosine cyclic 3':5'-monophosphate;n-(9-beta-d-ribofuranosyl-9h-furin-6-yl)-butyramide cyclic 3',5'-(hydrogen phosphate) 2'-butyrate;3',5'-Cyclic AMP dibutyrate;Cyclic AMP dibutyrate;Dibutyryl 3',5'-Cyclic AMP
CAS:362-74-3
MF:C18H24N5O8P
MW:469.39
EINECS:206-649-8
Product Categories:
Mol File:362-74-3.mol
Bucladesine Structure
Bucladesine Chemical Properties
density 1.72±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO; Methano
form Solid
pka0.82±0.60(Predicted)
color White
Safety Information
MSDS Information
Bucladesine Usage And Synthesis
DescriptionBucladesine is a cyclic nucleotide derivative that mimics the action of endogenous CYCLIC AMP and is capable of permeating the cell membrane. It has vasodilator properties and is used as a cardiac stimulant. (From Merck Index, 11th ed)
UsesBucladesine is a cell permeable cAMP analog. The compound is used in a wide variety of research applications because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions. cAMP is only able to elicit minimal responses in these situations. The neurite outgrowth instigated by bucladesine in cell cultures has been shown to be enhanced by nardosinone.
DefinitionChEBI: Bucladesine is a 3',5'-cyclic purine nucleotide that is the 2'-butanoate ester and 6-N-butanoyl derivative of 3',5'-cyclic AMP. It has a role as an agonist, a vasodilator agent and a cardiotonic drug. It is a butyrate ester, a 3',5'-cyclic purine nucleotide and a member of butanamides. It is functionally related to a 3',5'-cyclic AMP.
Bucladesine Preparation Products And Raw materials
Cephalosporin S-Adenosyl-L-methionine Losartan potassium L-ALPHA-PHOSPHATIDYLSERINES, BRAIN, BOVINE (S)-Amlodipine Oxiracetam Vinpocetine Dibutyryl adenosine cyclophosphate calcium N-ACETYLGLYCINAMIDE Pantoprazole Gastrodin Ambroxol Creatine phosphate disodium salt Bucladesine N6,2'-O-DISUCCINYLADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT Bucladesine sodium ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE, N6,O2'-DIOCTANOYL-, SODIUM SALT Cyclic AMP

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