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| 2-Methylhydroquinone Basic information |
| 2-Methylhydroquinone Chemical Properties |
Melting point | 128-130 °C(lit.) | Boiling point | 285°C | density | 1.1006 (rough estimate) | vapor pressure | 0.004Pa at 25℃ | refractive index | 1.4922 (estimate) | Fp | 172 °C | storage temp. | Store below +30°C. | solubility | 77g/l | pka | pK1:10.03;pK2:11.62 (25°C) | form | Crystalline Powder | color | Grayish-white to light beige | Water Solubility | 77 g/L (25 ºC) | BRN | 2041489 | Stability: | Stable. Combustible. Incompatible with oxidizing agents, strong bases. | InChIKey | CNHDIAIOKMXOLK-UHFFFAOYSA-N | LogP | 0.9 at 27℃ | CAS DataBase Reference | 95-71-6(CAS DataBase Reference) | NIST Chemistry Reference | 1,4-Benzenediol, 2-methyl-(95-71-6) | EPA Substance Registry System | 2-Methylhydroquinone (95-71-6) |
Hazard Codes | Xi,Xn | Risk Statements | 36/37/38-22 | Safety Statements | 26-36 | RIDADR | 2811 | WGK Germany | 2 | RTECS | MX6700000 | Autoignition Temperature | 851 °F | TSCA | Yes | HazardClass | 6.1(b) | PackingGroup | III | HS Code | 29072900 | Toxicity | LD50 orally in Rabbit: 200 - 400 mg/kg |
| 2-Methylhydroquinone Usage And Synthesis |
Chemical Properties | white solid | Uses | Antioxidant, polymerization inhibitor. | Uses | Methylhydroquinone is used as stabilizer and antioxidant in aerylic monomers to prevent polymerization. | Uses | Methylhydroquinone is a marine fungus metabolite, showing activity as an angiosupressor that interferes with the Akt pathway. Allows for screening of novel inhibitors of angiogenesis. | Definition | ChEBI: A member of the class of hydroquinones that is hydroquinone in which one of the benzene hydrogens has been replaced by a methyl group. | Synthesis Reference(s) | Tetrahedron, 44, p. 1227, 1988 DOI: 10.1016/S0040-4020(01)85902-0 Tetrahedron Letters, 22, p. 2337, 1981 DOI: 10.1016/S0040-4039(01)82900-2 | General Description | Methylhydroquinone is produced by the oxidation of o-cresol by the mutants G103S, G103S/A107G, and G103S/A107T. | Flammability and Explosibility | Notclassified | Biochem/physiol Actions | Methylhydroquinone (Toluquinol) inhibits the growth of endothelial and tumor cells in culture in the micromolar range and is a promising drug candidate in the treatment of cancer and other angiogenesis-related pathologies. | Purification Methods | Crystallise the quinone from EtOH. [Beilstein 6 IV 5866.] |
| 2-Methylhydroquinone Preparation Products And Raw materials |
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