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(Z)-4-HYDROXYTAMOXIFEN

(Z)-4-HYDROXYTAMOXIFEN Basic information
Product Name:(Z)-4-HYDROXYTAMOXIFEN
Synonyms:4-OH-TAM;TAMOXIFEN, (Z)-4-HYDROXY-;TAMOXIFEN, 4-HYDROXY-, (Z)-;(Z)-4-HYDROXYTAMOXIFEN;(Z)-4-[1-[4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL]-2-PHENYL-1-BUTENYL-PHENOL;(Z)-4-[1-(P-(DIMETHYLAMINOETHOXY)PHENYL)-2-PHENYL-1-BUTENYL]PHENOL;[Z]-1-[P-DIMETHYLAMINOETHOXYPHENYL]-1,2-DIPHENYL-1-BUTEN-4-OL;Phenol, 4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenyl-1-butenyl)-, (Z)-
CAS:65213-48-1
MF:C26H29NO2
MW:387.51
EINECS:
Product Categories:
Mol File:65213-48-1.mol
(Z)-4-HYDROXYTAMOXIFEN Structure
(Z)-4-HYDROXYTAMOXIFEN Chemical Properties
Melting point 137 - 143°C
storage temp. 2-8°C
solubility 95% ethanol: 20 mg/mL
form powder
color white
Stability:Light Sensitive
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-63
Safety Statements 22-23-36
WGK Germany 3
RTECS SL1210000
MSDS Information
ProviderLanguage
SigmaAldrich English
(Z)-4-HYDROXYTAMOXIFEN Usage And Synthesis
Uses(Z)-4-Hydroxy Tamoxifen is a metabolite of Tamoxifen (T006000). (Z)-4-Hydroxy Tamoxifen is a hydroxylated analogue of Tamoxifen. (Z)-4-Hydroxy Tamoxifen is a metabolite of Tamoxifen with anti-estrogenic properties.
DefinitionChEBI: Afimoxifene is a tertiary amino compound that is tamoxifen in which the phenyl group which is in a Z- relationship to the ethyl substituent is hydroxylated at the para- position. It is the active metabolite of tamoxifen. It has a role as an antineoplastic agent, an estrogen receptor antagonist and a metabolite. It is a tertiary amino compound and a member of phenols. It is functionally related to a tamoxifen.
(Z)-4-HYDROXYTAMOXIFEN Preparation Products And Raw materials
trans-4-Hydroxytamoxifen ,hydroxytamoxife N-Desmethyl-3-hydroxytamoxifen-d5,N-Desmethyl-3-hydroxytamoxifen-d5 3-hydroxytamoxife A-HYDROXYTAMOXIFEN,A-HYDROXYTAMOXIFEN N-DESMETHYL-4-HYDROXYTAMOXIFEN (1:1 E/Z MIXTURE),N-DESMETHYL-4-HYDROXYTAMOXIFEN (1:1 E/Z MIXTURE) (E)-4-Hydroxytamoxifen,(E)-4-Hydroxytamoxifen 4-HYDROXYTAMOXIFEN ETHYL-D5,4-HYDROXYTAMOXIFEN ETHYL-D5 4-ACETOXY TAMOXIFEN (Z)-4-HYDROXYTAMOXIFEN N-DESMETHYL-4-HYDROXYTAMOXIFEN-ETHYL-D5 (1:1 E/Z MIXTURE),N-DESMETHYL-4-HYDROXYTAMOXIFEN-ETHYL-D5 (1:1 E/Z MIXTURE) 4-HYDROXYTAMOXIFEN METHIODIDE,4-HYDROXYTAMOXIFEN METHIODIDE Desmethyl-4-hydroxytamoxifen-ethyl-5 (1:1 E/Z Mixture),Desmethyl-4-hydroxytamoxifen-ethyl-5 (1:1 E/Z Mixture) TAT 59 CIS-ALPHA-HYDROXYTAMOXIFEN,CIS-ALPHA-HYDROXYTAMOXIFEN B-HYDROXYTAMOXIFEN,B-HYDROXYTAMOXIFEN N-Desmethyl-3-Hydroxytamoxifen,N-Desmethyl-3-Hydroxytamoxifen cis-2-Methyl-4-hydroxytamoxifen,cis-2-Methyl-4-hydroxytamoxifen Nafoxidine
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