ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Other amino acid derivatives BOC-7-AMINO-HEPTANOIC ACID

BOC-7-AMINO-HEPTANOIC ACID

BOC-7-AMINO-HEPTANOIC ACID Basic information
Product Name:BOC-7-AMINO-HEPTANOIC ACID
Synonyms:BOC-AHEPT-OH;BOC-7-AHP-OH;BOC-7-AMINO-HEPTANOIC ACID;BOC-NH-(CH2)6-COOH;N-TERT-BUTYLOXYCARBONYL-7-AMINOHEPTANOIC ACID;7-(BOC-AMINO)ENANTHIC ACID;7-(BOC-AMINO)HEPTANOIC ACID;N-T-BUTOXYCARBONYL-7-AMINOENANTHIC ACID
CAS:60142-89-4
MF:C12H23NO4
MW:245.32
EINECS:
Product Categories:Unusual amino acids
Mol File:60142-89-4.mol
BOC-7-AMINO-HEPTANOIC ACID Structure
BOC-7-AMINO-HEPTANOIC ACID Chemical Properties
Melting point 56-60 °C
Boiling point 393.1±25.0 °C(Predicted)
density 1.050±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility soluble in Methanol
form powder to crystaline
pka4.77±0.10(Predicted)
color White to Almost white
BRN 2050867
CAS DataBase Reference60142-89-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
WGK Germany 3
F 9-21
HS Code 2922.50.5000
HazardClass IRRITANT
MSDS Information
ProviderLanguage
SigmaAldrich English
BOC-7-AMINO-HEPTANOIC ACID Usage And Synthesis
DescriptionBoc-7-Aminoheptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applicaitons. Boc-7-Aminoheptanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
BOC-7-AMINO-HEPTANOIC ACID Preparation Products And Raw materials
Preparation Products(7-Bromoheptyl)carbamic acid tert-butyl ester
FMOC-L-CIS/TRANS-CHA(4-NH-BOC) BOC-D-2-AMINOSUBERIC ACID (2S,4S)-N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N'-T-BUTYLOXYCARBONYL-2-PYRROLIDINYLALANINE METHYL N-BOC-3-PIPERIDINEPROPIONATE BOC-ASU-OH FMOC-D, L-HOMO[ALA-4-PIP(N-BOC)] BOC-ASU(OBZL)-OH DCHA BOC-1,2-TRANS-ACHC-OH N-A-CBZ-(2-N-BOC-PIPERIDINYL) GLYCINE (S)-A-FMOC-G-BOC-4-HOMO-PIPERIDYLALANINE BOC-7-AMINO-HEPTANOIC ACID 2-METHOXYCARBONYLMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER FMOC-L-BETA-HOMOLYSINE(BOC) BOC-1,2-CIS-ACHC-OH FMOC-D, L-CIS/TRANS-CHA(4-NH-BOC) FMOC-D, L-ALA(3-PYRROLIDINYL-(2-N-BOC)) N-Boc-2-piperidineacetic acid 3-(2-Carboxyethyl)piperidine-1-carboxylic acid tert-butyl ester
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