2-Thiophenecarbonyl chloride

2-Thiophenecarbonyl chloride Basic information

Product Name:	2-Thiophenecarbonyl chloride
Synonyms:	AKOS 92490;AKOS BBS-00003924;ALPHA-THENOYL CHLORIDE;THIOPHENE-2-CARBOXYLIC ACID CHLORIDE;THIOPHENE-2-CARBONYL CHLORIDE;TIMTEC-BB SBB004099;2-Thiophenzoyl Chloride;2-thienylcarbonyl chloride
CAS:	5271-67-0
MF:	C5H3ClOS
MW:	146.59
EINECS:	226-092-4
Product Categories:	Building Blocks;C4 to C6;ACIDHALIDE;Chemical Synthesis;Heterocyclic Building Blocks;Thiophenes;Thiophene&Benzothiophene;Heterocyclic Compounds
Mol File:	5271-67-0.mol

2-Thiophenecarbonyl chloride Chemical Properties

Boiling point	206-208 °C (lit.)
density	1.371 g/mL at 25 °C (lit.)
refractive index	n20/D 1.590(lit.)
Fp	195 °F
storage temp.	2-8°C
solubility	Chloroform
form	Liquid
color	Clear colorless to yellow-gray
Specific Gravity	1.371
Sensitive	Moisture Sensitive
BRN	110145
InChIKey	QIQITDHWZYEEPA-UHFFFAOYSA-N
CAS DataBase Reference	5271-67-0(CAS DataBase Reference)
NIST Chemistry Reference	2-Thiophenecarbonyl chloride(5271-67-0)
EPA Substance Registry System	2-Thiophenecarbonyl chloride (5271-67-0)

Safety Information

Hazard Codes	C
Risk Statements	34-37
Safety Statements	26-36/37/39-45
RIDADR	UN 3265 8/PG 2
WGK Germany	3
F	8
TSCA	Yes
HazardClass	8
PackingGroup	II
HS Code	29349990

MSDS Information

Provider	Language
Thiophene-2-carbonyl chloride	English
SigmaAldrich	English
ACROS	English
ALFA	English

2-Thiophenecarbonyl chloride Usage And Synthesis

Chemical Properties	CLEAR COLOURLESS TO YELLOW-GREY LIQUID
Uses	2-Thiophenecarbonyl Chloride is used in the synthesis of substituted pyridines as selective and highly effective GPR119 agonists. It is also seen in the preparation of diuretics.
Uses	2-Thiophenecarbonyl chloride was used in the synthesis of building blocks derived from ornithine by undergoing acylation/sulphonation of copper complex of orthinine.
General Description	The postfunctionalization reaction of 2-thiophenecarbonyl chloride with single walled carbon nanotubes (SWCNTs) was studied.

2-Thiophenecarbonyl chloride Preparation Products And Raw materials

Raw materials	4-Iodobenzoyl chloride-->2-Iodothiophene-->Terephthaloyl chloride
Preparation Products	ETHYL 2-[(2-THIENYLCARBONYL)AMINO]ACETATE-->2-Thienyl isocyanate-->Thiophene-2-carboxylic acid fluoride-->2-N-BUTYRYLTHIOPHENE-->tioxazafen-->2-BENZOYLTHIOPHENE-->BIS(2-THIENYL) KETONE-->2-(TRIFLUOROACETYL)THIOPHENE-->6,7-DIMETHOXY-2-(2-THIENYL)-4H-3,1-BENZOXAZIN-4-ONE-->ethyl 2-(thiophene-2-carboxamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate

Methylene Chloride 4-Nitrobenzoyl chloride PYRAZOPHOS Calcium chloride Sodium chloride 4-tert-Butylbenzoyl chloride CARBONYL SULFIDE Thiophene Choline chloride Methanesulfonyl chloride Sulfuryl chloride Ammonium chloride Polyvinyl chloride 4-Chlorobenzoyl chloride Benzoyl chloride Potassium chloride 2-[[(2-ethylphenyl)(2-hydroxyethyl)amino]methyl]-3,3-difluoro-Propanenitrile p-Toluoyl chloride

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