1,3-Benzodioxole

1,3-Benzodioxole Basic information
Product Name:1,3-Benzodioxole
Synonyms:1,2- Methylenetwophenoxy;Anti-ABR (C-terminal) antibody produced in rabbit;FLJ45954;1,2-Methylenedioxybenzene 1,3-Benzodioxole;1,2-methylenedioxy-benzen;1,3-Dioxaindan;1,3-Dioxindan;2h-1,3-benzodioxole
CAS:274-09-9
MF:C7H6O2
MW:122.12
EINECS:205-992-0
Product Categories:Aromatic Ethers;274-09-9
Mol File:274-09-9.mol
1,3-Benzodioxole Structure
1,3-Benzodioxole Chemical Properties
Melting point -18 °C
Boiling point 172-173 °C(lit.)
density 1.064 g/mL at 25 °C(lit.)
vapor pressure 12 mm Hg ( 25 °C)
refractive index n20/D 1.539(lit.)
Fp 131 °F
storage temp. Inert atmosphere,Room Temperature
solubility 2g/l
form Powder
color Yellow to orange to brown
Water Solubility 0.2 g/100 mL (25 ºC)
BRN 115506
InChIKeyFTNJQNQLEGKTGD-UHFFFAOYSA-N
LogP2.08
CAS DataBase Reference274-09-9(CAS DataBase Reference)
NIST Chemistry Reference1,3-Benzodioxole(274-09-9)
EPA Substance Registry System1,3-Benzodioxole (274-09-9)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 20/22-22-10-36/37/38-20/21/22-10/22
Safety Statements 23-24/25-36/37/39-26-16-36
RIDADR UN 1993 3/PG 3
WGK Germany 3
RTECS DA5600000
Hazard Note Irritant
TSCA Yes
HazardClass 3
PackingGroup III
HS Code 29329970
MSDS Information
ProviderLanguage
1,2-(Methylenedioxy)benzene English
SigmaAldrich English
ACROS English
ALFA English
1,3-Benzodioxole Usage And Synthesis
Description1,3-Benzodioxole, widely found in plant products, has shown potent antioxidant and antibacterial activities. It has recently been reported that 1,3-benzodioxole derivatives possess cytotoxic activity against several human tumor cell lines, including human colon carcinoma cells and multidrug-resistant nasopharyngeal carcinoma cells. No cytotoxic effects were noticed at a concentration of 10-4 M.
Chemical Propertiesclear colourless to light yellow liquid. Insoluble in acids.
Uses1,3-Benzodioxole is useful in gemological stimulant detection. It is also used as a precursor for perfumes, photo initiators, agrochemicals and pharmaceuticals. 1,3-benzodimine is an intermediate for the synthesis of the drugs oxolinic acid, cinoxacin and miloxacin.
Application1,3-Benzodioxole belong to methylenedioxyphenyl (MDP) compounds that regulate cytochrome P 450-dependent drug oxidation, which is important in the process of eliminating drugs from the body. a hydrogen abstraction process can take place from the methylene-bridgea carbon of the benzodioxole compound and form a methylenedioxybenzene radical. It is therefore highly likely that 1,3-benzodioxole could serve as hydrogen donor for a CQ-based system initiating the photopolymerization of dental composite resin. In addition, 1,3-benzodioxole is an important organic intermediate (building block) to synthetize substituted methylenedioxybenzene products.
DefinitionChEBI: 1,3-benzodioxole is a benzodioxole consisting of a benzene ring substituted by a the methylenedioxy group.
General DescriptionSupersonic jet fluorescence spectra of 1,3-benzodioxole has been studied. The far-infrared spectrum of the vapour of 1,3-benzodioxole has been reported. The electronic absorption spectra and the laser-induced fluorescence spectra of supersonic-jet-cooled 1,3-benzodioxole molecules has been investigated.
6-AMINO-1,3-BENZODIOXOLE-5-CARBOXYLIC ACID A-METHYL-1,3-BENZODIOXOLE-5-PROPIONALDEHYDE N-Methylparoxetine 7-CHLORO-1,3-BENZODIOXOLE-5-CARBOXYLIC ACID Methyl cyclopentenolone PAROXETINE-D4 HCL 4-Methoxybenzyl cyanide m-Anisyl alcohol 5-NITRO-6-TRIFLUOROMETHYL-1,3-BENZODIOXOLE-2-ONE DIOXOPROMETHAZINE 1,3-BENZODIOXOLE-4-CARBALDEHYDE 5-[(OXIRAN-2-YLMETHOXY)METHYL]-1,3-BENZODIOXOLE 6-NITRO-1,3-BENZODIOXOLE-5-CARBALDEHYDE OXIME 6-NITRO-4-TRIFLUOROMETHYL-1,3-BENZODIOXOLE-2-ONE ALPHA-HYDROXY-1,3-BENZODIOXOLE-5-ACETIC ACID 6-BROMO-1,3-BENZODIOXOLE-5-CARBALDEHYDE O-(2,4-DICHLOROBENZYL)OXIME 6,7-DIMETHOXY-1,3-BENZODIOXOLE-5-CARBALDEHYDE N-(1-[2-(4-CHLOROPHENYL)ETHYL]PIPERIDIN-4-YL)-N-(2-FURYLMETHYL)-1,3-BENZODIOXOLE-5-CARBOXAMIDE

Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.