Acriflavine hydrochloride

Acriflavine hydrochloride Basic information
Product Name:Acriflavine hydrochloride
Synonyms:LISTERIA SELECTIVE SUPPLEMENT UVM-II;LISTERIA PALCAM SELECTIVE SUPPLEMENT;EUFLAVIN HYDROCHLORIDE;CI 46000;Acriflavine DiHCl (Mixture of AcriflaviniuM Chloride with Proflavine);Acriflavine Hydrochloride (>90%);Acriflavine hydrochloride, Intercalating dye, antiseptic, analysis of cellular DNA and protein;ACRIFLAVINE HYDROCHLORIDE
CAS:8063-24-9
MF:C27H28Cl4N6
MW:578.36
EINECS:1312995-182-4
Product Categories:8063-24-9
Mol File:8063-24-9.mol
Acriflavine hydrochloride Structure
Acriflavine hydrochloride Chemical Properties
Melting point 260 °C
storage temp. +2°C TO
solubility H2O: soluble1mg/mL
form Powder
color Red-brown
PH Range2
Water Solubility Soluble in water, dimethyl sulfoxide and methanol.
Merck 123
BRN 6265525
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyVWXAJKFSYJFBIW-UHFFFAOYSA-N
Safety Information
Hazard Codes N-Xn,N,Xn
Risk Statements 51/53-41-22-20/21/22
Safety Statements 61-39-29-26-36
RIDADR UN 3077 9/PG 3
WGK Germany 2
HazardClass 9
PackingGroup III
HS Code 38249064
MSDS Information
ProviderLanguage
ACROS English
Acriflavine hydrochloride Usage And Synthesis
Chemical Propertiesreddish-brown crystalline powder
UsesAcriflavine is an topical antiseptic agent and has also been used for the treatment of external fungal infections.
UsesAcriflavine Hydrochloride acts as an intercalating dye and also reported to inhibit mitochondriogenesis. It is an antiseptic and has been used in applications for dual fluorescence analysis of cellular DNA and protein simultaneously.
Purification MethodsPurify it by dissolving in 50 parts of H2O, shaking with a small excess of freshly precipitated and washed Ag2O. The mixture is set aside overnight at 0o and filtered. The cake is not washed. The pH of the filtrate is adjusted to 7.0 with HCl and evaporated to dryness. The residue is then crystallised twice from MeOH, twice from H2O and dried at 120o. at 452nm has a log value of 4.67. Itis ared max powder which readily absorbs H2O. The solubility is increased in the presence of proflavin. The dihydrochloride is a deep red crystalline powder. It is available as a mixture of 3,6-diaminoacridinium chloride (35%) and its 10-metho-chloride (65%). [See Albert, The Acridines Arnold Press p 346 1966, Benda Chem Ber 45 1787 1912]. [Beilstein 23 I 650.]
Acriflavine hydrochloride Preparation Products And Raw materials
2 8-DIAMINO-10-METHYLACRIDINIUM CHLORIDE HYDROCHLORIDE Euflavine, 3,6-Diamino-10-methylacridinium chloride mixt. with 3,6-diaminoacridine (proflavine),EUFLAVINE ACRIFLAVINE HYDROCHLORIDE--N Tris(2,4-pentanedionato)chroMiuM(III) DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Topotecan hydrochloride Sibutramine hydrochloride Tramadol hydrochloride 2,4-PENTANEDIONE, SILVER DERIVATIVE ACRIFLAVINE HYDROCHLORIDE COBALT(II) ACETYLACETONATE SCINTIVERSE BD COCKTAIL Cupric acetylacetonate 1-AdaMantanethylaMine Ferric acetylacetonate COBALT ETHYLENE DIAMINE CHLORIDE Acrifiavine hydrochloride EUFLAVINE (ACRIFLAVINE) Acriflavine Hcl

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