ChemicalBook Product Catalog Organic Chemistry Heterocyclic Compounds 5-Bromoindole

5-Bromoindole

5-Bromoindole Basic information
Product Name:5-Bromoindole
Synonyms:5-BROMOINDOLE;5-BI;5-Bromindole;5-bromonindole;5-Bromide indole;Bromoindole-99%;5-Bromoindole99%;5-Bromoindole 99%
CAS:10075-50-0
MF:C8H6BrN
MW:196.04
EINECS:233-208-7
Product Categories:Halogenated Heterocycles;Heterocyclic Building Blocks;IndolesBuilding Blocks;Organohalides;Simple Indoles;Pyrroles & Indoles;Heterocycle-Indole series;Indoles;Pharmaceutical Intermediates;Indole Derivatives;Indole/indoline/oxindole;Indoles and derivatives;IndoleDerivative;Halides;Pyrroles & Indoles;Indole;blocks;Bromides;IndolesOxindoles;bc0001
Mol File:10075-50-0.mol
5-Bromoindole Structure
5-Bromoindole Chemical Properties
Melting point 90-92 °C (lit.)
Boiling point 228.5°C (rough estimate)
density 1.5466 (rough estimate)
refractive index 1.6550 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 126mg/l (calculated)
form Powder or Chunks
pka16.04±0.30(Predicted)
color White to light brown
BRN 112877
InChIKeyVXWVFZFZYXOBTA-UHFFFAOYSA-N
CAS DataBase Reference10075-50-0(CAS DataBase Reference)
EPA Substance Registry System1H-Indole, 5-bromo- (10075-50-0)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25-37/39
WGK Germany 3
Hazard Note Irritant
HS Code 29339990
MSDS Information
ProviderLanguage
5-Bromo-1H-indole English
SigmaAldrich English
ACROS English
ALFA English
5-Bromoindole Usage And Synthesis
Chemical Propertieswhite to light brown powder or chunks
UsesA potential inhibitor of GSK-3
Purification MethodsPurify it by steam distillation from a faintly alkaline solution. Cool the aqueous distillate, collect the solid, dry it in a vacuum desiccator over P2O5 and recrystallise it from aqueous EtOH (35% EtOH) or pet ether/Et2O. UV in MeOH has at 279, 287 and 296nm (log 3.70, 3.69 and 3.53). The picrate has m 137-138o(dec) (from max Et2O/pet ether). [UV: Thesing et al. Chem Ber 95 2205 1962, UV and NMR: Lallemand & Bernath Bull Soc Chim Fr 4091 1970, Beilstein 20/7 V 36.]
5-Bromoindole Preparation Products And Raw materials
Preparation Products1-METHYL-1H-INDOLE-5-BORONIC ACID 2,2-DIMETHYL PROPANE DIOL-1,3-CYCLIC ESTER-->C-(1H-INDOL-5-YL)-METHYLAMINE-->5-Indolylboronic acid-->5-Cyanoindole-->5-Acetylindole-->Indole-5-carboxaldehyde-->5-Bromoisatoic anhydride-->(R)-5-BROMO-3-[(1-METHYL-2-PYRROLIDINYL)METHYL]-1H-INDOLE-->INDOLE-5-METHANOL-->5-Bromo-1-(tert-butoxycarbonyl)-1H-indol-2-ylboronic acid-->1-METHYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDOLE-->3-ACETOXY-5-BROMOINDOLE-->5-Bromo-3-cyanoindole
3-ACETOXY-5-BROMOINDOLE 5-BROMO-4-CHLORO-3-INDOLYL ACETATE 2-[2'-NITROPHENYLSULFENYL]-3-METHYL-3-BROMOINDOLE 7-AMINO-5-BROMOINDOLE 3-Acetyl-5-bromoindole 5-BROMOINDOLE-3-ACETAMIDE 4-BENZYLOXY-3-BROMOINDOLE, N-BOC PROTECTED,4-BENZYLOXY-3-BROMOINDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 3-BROMOINDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER,3-BROMOINDOLE, N-BOC PROTECTED 5-BROMOINDOXYL DIACETATE 1-Acetyl-5-bromo-4-chloro-1H-indol-3-yl acetate 5-BROMO-6-CHLORO-3-INDOXYL-3-ACETATE 7-Bromo-1H-indole, N-BOC protected 3-BROMOINDOLE-2-CARBOXYLIC ACID ETHYL ESTER bromo-Dragonfly 5-BROMOINDOLE-3-ACETIC ACID HYDRAZIDE 1H-PYRIDO[3,4-B]INDOLE, 6-BROMO-2,3,4,9-TETRAHYDRO- X-GLUC 6-BROMOINDOLE
Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.