|
| (-)-Denudatin B Basic information |
Product Name: | (-)-Denudatin B | Synonyms: | (-)-Denudatin B;C10554;(2S,3R,3aS)-2-(3,4-dimethoxyphenyl)-3a-methoxy-3-methyl-5-prop-2-enyl-2,3-dihydrobenzofuran-6-one;(-)-Denudatin B;6(2H)-Benzofuranone, 2-(3,4-dimethoxyphenyl)-3,3a-dihydro-3a-methoxy-3-methyl-5-(2-propen-1-yl)-, (2S,3R,3aR)- | CAS: | 87402-88-8 | MF: | C21H24O5 | MW: | 356.41 | EINECS: | | Product Categories: | | Mol File: | 87402-88-8.mol | |
| (-)-Denudatin B Chemical Properties |
Boiling point | 491.1±45.0 °C(Predicted) | density | 1.18±0.1 g/cm3(Predicted) | storage temp. | 4°C, away from moisture and light |
| (-)-Denudatin B Usage And Synthesis |
Definition | ChEBI: Denudatin B is a member of benzofurans. | Biological Activity | (-)-Denudatin B is an antiplatelet agent. (-)-Denudatin B relaxed vascular smooth muscle by inhibiting the Ca2+ influx through voltage-gated and receptor-operated Ca2+ channels[1]. And (-)-Denudatin B has nonspecific antiplatelet action | References | [1]. Yu SM,et al. Vasorelaxing effect in rat thoracic aorta caused by denudatin B, isolated from the Chinese herb, magnolia fargesii. Eur J Pharmacol. 1990;187(1):39-47. [2]. Teng CM, et al. Inhibition of thrombin- and collagen-induced phosphoinositides breakdown in rabbit platelets by a PAF antagonist--denudatin B, an isomer of kadsurenone. Thromb Res. 1990;59(1):121-130. |
| (-)-Denudatin B Preparation Products And Raw materials |
|