ChemicalBook Product Catalog Natural Products Coumarin FRAXINOL

FRAXINOL

FRAXINOL Basic information
Product Name:FRAXINOL
Synonyms:FRAXINOL;5,7-Dimethoxy-6-hydroxycoumarin;6-Hydroxy-5,7-dimethoxy-2H-1-benzopyran-2-one;6-Hydroxy-5,7-dimethoxycoumarin;Fraxil;6-Hydroxy-5,7-dimethoxy-chromen-2-one;6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one;2H-1-Benzopyran-2-one, 6-hydroxy-5,7-dimethoxy-
CAS:486-28-2
MF:C11H10O5
MW:222.19
EINECS:
Product Categories:
Mol File:486-28-2.mol
FRAXINOL Structure
FRAXINOL Chemical Properties
Melting point 170-172℃
Boiling point 449.7±45.0 °C(Predicted)
density 1.358
storage temp. Store at -20°C
solubility Soluble in DMSO and methanol;
form powder
pka8.95±0.20(Predicted)
color White-yellowish
Water Solubility slightly soluble in water
CAS DataBase Reference486-28-2
Safety Information
MSDS Information
FRAXINOL Usage And Synthesis
DescriptionFraxinol is a coumarin originally isolated from Ash tree bark. It inhibits growth of GLC-4 small cell lung carcinoma and COLO 320 colorectal cancer cells (IC50s = 193 and 165 μM, respectively). Fraxinol potentiates barbiturate-induced sleep in rats and rabbits.
FRAXINOL Preparation Products And Raw materials
4-Hydroxycoumarin 6-ISOPENTENYLOXYISOBERGAPTEN WEDELOLACTONE 5,7-Dihydroxy-4-methylcoumarin pimpinellin ISOBERGAPTOL 4-METHYLESCULETIN MURRAYAE FOLIUM ET CACUMEN 5,8-DIHYDROXYPSORALEN MEDICAGOL 5-Hydroxyxanthotoxin FRAXIN 5,7-Dimethoxycoumarin
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