RS 42358-197

RS 42358-197 Basic information
Product Name:RS 42358-197
Synonyms:RS 42358-197;2-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl] 2,4,5,6-tetrahydro-1H-benzo[de]isoquinolin-1-one hydrochloride;Palonosetron Hydrochloride Impurity 1;Palonosetron Impurity 1 HCl;Palonosetron USP Related Compound E;(S)-2-(quinuclidin-3-yl)-2,4,5,6-tetrahydro-1H-benzo[de]isoquinolin-1-one hydrochloride;2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-5,6-dihydro-4~{H}-benzo[de]isoquinolin-1-one;Palonosetron-3-ene Hydrochloride
CAS:135729-55-4
MF:C19H23ClN2O
MW:330.86
EINECS:
Product Categories:
Mol File:135729-55-4.mol
RS 42358-197 Structure
RS 42358-197 Chemical Properties
Melting point >160°C
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Methanol (Slightly), Water (Slightly)
form Solid
color Off-White to Yellow
Safety Information
HS Code 2933790002
MSDS Information
RS 42358-197 Usage And Synthesis
UsesPalonosetron-3-ene Hydrochloride is an impurity of Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
ApplicationPalonosetron-3-ene Hydrochloride is an impurity of Palonosetron, a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
RS 42358-197 Preparation Products And Raw materials
Palonosetron Hydrochloride 1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- Palonosetron Impurity 12 Palonosetron Impurity 7 Palonosetron Impurity 11 (R,S)-Palonosetron Hydrochloride (S,R)-Palonosetron Hydrochloride Palonosetron impurity Palonosetron Impurity 8 PALONOSETRON HCL 1H-Benz[de]isoquinolin-1-one,2-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-,(3aS)- (3S)-N-[[(1S)-1,2,3,4-Tetrahydro-1-naphthalenyl]Methyl]-1-azabicyclo[2.2.2]octan-3-aMine Palonosetron Palonosetron Impurity 9 1H-Benz[de]isoquinolin-1-one,2-(3S)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-,(3aR)- Palonosetron N-Oxide (1S)-N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxaMide GIIYMZHZCASHNL-NVXWUHKLSA-N

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