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| | toddalolactone Basic information |
| Product Name: | toddalolactone | | Synonyms: | toddalolactone;6-(2,3-Dihydroxy-3-methylbutyl)-5,7-dimethoxy-2H-1-benzopyran-2-one;Toddaline;(+)-Toddalolactone;6-[(2R)-2,3-dihydroxy-3-methyl-butyl]-5,7-dimethoxy-chromen-2-one;6-[(2R)-2,3-dihydroxy-3-methylbutyl]-5,7-dimethoxychromen-2-one;6-[(2R)-2,3-dihydroxy-3-methyl-butyl]-5,7-dimethoxy-coumarin;Toddaloactone | | CAS: | 483-90-9 | | MF: | C16H20O6 | | MW: | 308.33 | | EINECS: | | | Product Categories: | | | Mol File: | 483-90-9.mol |  |
| | toddalolactone Chemical Properties |
| Melting point | 269-270°C | | Boiling point | 530.0±50.0 °C(Predicted) | | density | 1.269±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 14.39±0.20(Predicted) |
| | toddalolactone Usage And Synthesis |
| Description | Toddalia aculeata Pers. (Rutaceae) contains, in addition to Berberine (q.v.), two
closely related alkaloids. This particular base forms colourless crystals from
CHC13 and is characterized as the hydrochloride monohydrate, m.p. 205-6°C;
nitrate, yellow needles, m.p. 239° C (dec.) and the picrate, glancing needles,
m.p. 237-8°C. Two methoxyl groups and a methylimino group have been
shown to be present. | | Uses | Toddalolactone is a prenylated coumarin which acts as a natural phosphodiesterase-4 inhibitor. Antiplasmodial and larvicidal agent. | | References | Dey, Pillay., Arch. Pharm., 271,477 (1933)
Dey et al., Ind. J. Med. Res., 22,765 (1935)
Lobstein, Hesse., Bull. Sci. Pharmacol., 38, 157 (1931) |
| | toddalolactone Preparation Products And Raw materials |
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