Phthalhydrazide

Phthalhydrazide Basic information
Product Name:Phthalhydrazide
Synonyms:PHTALYLHYDRAZINE;PHTHALHYDRAZIDE;PHTHALHYDRAZINE;PHTHALIC HYDRAZIDE;PHTHALOYLHYDRAZINE;1,4-Ketophthalazine;1,4-phthalazinediol;2,3-dihydro-4-phthalazinedione
CAS:1445-69-8
MF:C8H6N2O2
MW:162.15
EINECS:215-893-4
Product Categories:
Mol File:1445-69-8.mol
Phthalhydrazide Structure
Phthalhydrazide Chemical Properties
Melting point >300 °C (lit.)
Boiling point 288.82°C (rough estimate)
density 1.3264 (rough estimate)
refractive index 1.5770 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Soluble in acetone and acetic acid.
pka10.70±0.20(Predicted)
form Powder and Chunks
color White
BRN 135926
InChIKeyKGLPWQKSKUVKMJ-UHFFFAOYSA-N
CAS DataBase Reference1445-69-8(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
RTECS TH8890080
HS Code 29280000
Toxicitymouse,LD50,intraperitoneal,700mg/kg (700mg/kg),Archiv der Pharmazie Vol. 327, Pg. 237, 1994.
MSDS Information
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Phthalhydrazide English
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Phthalhydrazide Usage And Synthesis
Chemical PropertiesWHITE POWDER AND CHUNKS
UsesPhthalic Hydrazide is a reagent in the synthesis in various pyrazolophthalazine derivatives.
UsesPhthalhydrazide is a reagent used in the synthesis of various pyrazolophthalazine derivatives is and used in medicine double hydrazine phthalocyanine work intermediates.
Synthesis Reference(s)Journal of Heterocyclic Chemistry, 5, p. 111, 1968 DOI: 10.1002/jhet.5570050120
Synthesis Reference(s)Journal of the American Chemical Society, 84, p. 966, 1962 DOI: 10.1021/ja00865a018
Purification MethodsRecrystallise it twice from 0.1M KOH [Merenyi et al. J Am Chem Soc 108 7716 1986], EtOH or dimethylformamide and it sublimes >300o. [Beilstein 24 H 371, 24 II 194.]
LUMINOLSODIUM 6-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE,6-AMINO-2-3-DIHYDRO-1-4-PHTHALAZINEDIONE CRYSTALLI Luminol O-Phthalimide 2-(3-chloropropyl)-3-phenyl-2,3-dihydro-1,4-phthalazinedione 2-(3-CHLOROPROPYL)-3-METHYL-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE Benzoyl hydrazine METHYL 3-(1,4-DIOXO-3,4-DIHYDROPHTHALAZIN-2(1H)-YL)PROPANOATE Phthalhydrazide 1,4-PHTHALAZINEDIONE,2,3-DIHYDRO-5-NITRO,2,3-dihydro-5-nitro-4-phthalazinedion SPECS AJ-292/41083387 3-(1,4-DIOXO-3,4-DIHYDROPHTHALAZIN-2(1H)-YL)-N-PENTYLPROPANAMIDE 1,4-Phthalazinedione, 2,3-dihydro-6-nitro.,2,3-dihydro-6-nitro-4-phthalazinedion 2,3-DIBENZYL-2,3-DIHYDROPHTHALAZINE-1,4-DIONE BPST CHLORIDE 6-[N-(4-AMINOBUTYL)-N-ETHYLAMINO]-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE 1,5-Diphenylcarbazide 3-(1,4-DIOXO-3,4-DIHYDRO-1H-PHTHALAZIN-2-YL)-PROPIONIC ACID

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