ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards (2-PHENOXY)METHYLSULFONYLANILINE

(2-PHENOXY)METHYLSULFONYLANILINE

(2-PHENOXY)METHYLSULFONYLANILINE Basic information
Product Name:(2-PHENOXY)METHYLSULFONYLANILINE
Synonyms:2-PHENOXYMETHANESULFOANILIDE;2-PHENOXYMETHANESULFONANILIDE;Nimesulide EP Impurity B,(N-（2-phenoxyphenyl)methanesulfonamide);(2-PHENOXY)METHYLSULFONYLANILINE;N-(2-phenoxyphenyl)methanesulphonamide;2-Phenoxymethanesulfonailide;Einecs 257-399-1;Nimesulide impurity-B(EP/BP)
CAS:51765-51-6
MF:C13H13NO3S
MW:263.31
EINECS:257-399-1
Product Categories:
Mol File:51765-51-6.mol
(2-PHENOXY)METHYLSULFONYLANILINE Structure
(2-PHENOXY)METHYLSULFONYLANILINE Chemical Properties
Melting point 126℃
Boiling point 378.9±44.0 °C(Predicted)
density 1.313
vapor pressure 0Pa at 25℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Slightly), DMSO
form Solid
pka8.43±0.10(Predicted)
color White to Off-White
Water Solubility 176.1mg/L at 25℃
LogP2.4 at 25℃
Safety Information
MSDS Information
(2-PHENOXY)METHYLSULFONYLANILINE Usage And Synthesis
Uses2''-Phenoxymethanesulfonanilide is a metabolite of nimesulide (N477500), which is an antiinflammatory agent. It preferentially inhibits COX-2 over COX-1 and suppresses chemical-induced carcinogenesis in mice and rats. Nimesulide also nhibits LPS-induced TNF-alpha production.
(2-PHENOXY)METHYLSULFONYLANILINE Preparation Products And Raw materials
Preparation ProductsNimesulide
4-Nitro-2-phenoxyaniline NiMesulide EP IMpurity E N-(Methylsulfonyl)-4'-nitro-2'-phenoxyMethanesulfonanilide TRIFLUOROMETHANESULFONYL CHLORIDE 4',6'-Dinitro-2'-phenoxymethanesulfonanilide 2-Phenoxyaniline 4-Nitro-2-phenoxyphenol NiMesulide EP IMpurity N-[4-nitro-2-(2,3,4,5,6-pentadeuteriophenoxy)phenyl]methanesulfonamide Nimesulide [(Methylsulfonyl)(2-phenoxyphenyl)amino]-acetic acid 4-HYDROXY NIMESULIDE (2-PHENOXY)METHYLSULFONYLANILINE Flosulide ((4-CHLORO-2-NITROPHENYL)SULFONYL)(2-PHENOXYPHENYL)AMINE Iguratimod FK-3311 AKOS 91918
Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.