ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]-

L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]-

L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]- Basic information
Product Name:L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]-
Synonyms:Methotrexate EP Impurity C（Amethopterin EP Impurity C）;Methotrexate-EP-Imp-C;L-Glutamic acid,N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-;Methotrexate EP Impurity C/Methotrextae 4-Oxo Analog/N-Methylfolic acid/(2S)-2-[[4-[[(2-amino-4-hydroxy pteridin-6-yl)methyl]methyl amino] benzoyl]amino]pentanedioic acid;Methotrexate Related CoMpound C;(2S)-2-[[4-[[(2-amino-4-hydroxy pteridin-6-yl) methyl] methyl amino] benzoyl] amino] pentanedioic acid;2-[[4-[(2-Amino-4-Oxo-1H-Pteridin-6-Yl)Methyl-Methylamino]Benzoyl]Amino]Pentanedioic Acid;L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]-
CAS:2410-93-7
MF:C20H21N7O6
MW:455.42
EINECS:
Product Categories:
Mol File:2410-93-7.mol
L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]- Structure
L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]- Chemical Properties
Melting point 144 - 150°C
density 1.61±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMF (Slightly, Heated), DMSO (Slightly)
form neat
pka3.49±0.10(Predicted)
color Pale Brown to Brown
Safety Information
RIDADR UN 2811 6.1 / PGIII
HS Code 2933599550
MSDS Information
L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]- Usage And Synthesis
Uses2-[(2-Hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxylic Acid is an impurity of Acotiamide (A190260), an acetylcholinesterase inhibitor which has been shown to stimulate gastric motility and improve gastric motility dysfunction in rats. Acotiamide Hydrochloride has also been shown to improve meal-related symptoms of functional dyspepsia.
DefinitionChEBI: Methopterine is a member of folic acids.
L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]- Preparation Products And Raw materials
4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid Methotrexate 2,4-DIAMINO-6-(HYDROXYMETHYL)PTERIDINE Methotrexate EP Impurity G 6-(Bromomethyl)-2,4-pteridinediamine hydrobromide N-(4-(METHYLAMINO)BENZOYL)-L-GLUTAMIC ACID Aminopterin Methotrexate Related Compound E (50 mg) (4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzoic acid, hemihydrochloride) D(-)-AMETHOPTERIN L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]- 4-HYDROXYPTERIDINE
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