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| | N4-Benzoylcytosine Basic information |
| | N4-Benzoylcytosine Chemical Properties |
| Melting point | >300 °C (dec.) (lit.) | | density | 1.33±0.1 g/cm3(Predicted) | | vapor pressure | 0Pa at 25℃ | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | Aqueous Acid (Slightly, Heated), DMSO+DCl (Slightly, Heated) | | form | Solid | | pka | 7.75±0.10(Predicted) | | color | Off-White | | InChI | InChI=1S/C11H9N3O2/c15-10(8-4-2-1-3-5-8)13-9-6-7-12-11(16)14-9/h1-7H,(H2,12,13,14,15,16) | | InChIKey | XBDUZBHKKUFFRH-UHFFFAOYSA-N | | SMILES | C(NC1=CC=NC(=O)N1)(=O)C1=CC=CC=C1 | | Surface tension | 72.2mN/m at 1g/L and 21.2℃ | | CAS DataBase Reference | 26661-13-2(CAS DataBase Reference) |
| | N4-Benzoylcytosine Usage And Synthesis |
| Chemical Properties | White or almost white crystalline powder | | Uses | N4-Benzoylcytosine may be employed for the following syntheses:
- 3′-C-ethynyl and 3′-C-(1,4-disubstituted-1,2,3-triazolo) double-headed pyranonucleosides
- 2′-C-methyl-4′-thiocytidine, via the Pummerer reaction
- 2′-fluorinated L-nucleoside analogs
| | Uses | N4-Benzoylcytosine is a reactant in the synthesis of 1'',2''-cyclopentyl nucleosides as potential antiviral agents. | | General Description | N4-Benzoylcytosine is an amide and its anti-microbial activity against pathogenic microorganisms has been studied using the Disk Diffusion and the Pour Plate method. It can be synthesized via the condensation of benzoyl chloride with cytosine. |
| | N4-Benzoylcytosine Preparation Products And Raw materials |
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