|
| Product Name: | ABD-F | | Synonyms: | 4-Fluoro-7-sulfobenzofurazan;[=4-(AMinosulfonyl)-7-fluoro-2,1,3-benzoxadiazole] [HPLC Labeling Reagent for DeterMination of Thiols];ABD-F ;4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazol;4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazol, 98%, derivatization grade;7-Fluorobenzoc1,2,5oxadiazole-4-sulfonamide;4-(AMinosulfonyl)-7-fluoro-2,1,3-benzoxadiazol, derivatization grade;ABD-F | | CAS: | 91366-65-3 | | MF: | C6H4FN3O3S | | MW: | 217.18 | | EINECS: | | | Product Categories: | Chemical and pharmaceutical intermediates;pharmaceutical intermediates;Analytical Chemistry;Fluorescence Detection (HPLC Labeling Reagents);HPLC Labeling Reagents;Mercapto Group Labeling Reagents for Fluorescence HPLC;Fluorescent Labels and Indicators;Fluorescent Labels & Indicators;MTS & Sulfhydryl Active Reagents | | Mol File: | 91366-65-3.mol |  |
| | ABD-F Chemical Properties |
| Melting point | 143-145°C | | Boiling point | 408.8±55.0 °C(Predicted) | | density | 1.724±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMSO: soluble | | pka | 9.08±0.30(Predicted) | | form | White to yellow crystalline powder. | | color | Off-White to Pale Yellow | | BRN | 5035147 | | Stability: | Light Sensitive | | InChIKey | XROXHZMRDABMHS-UHFFFAOYSA-N |
| | ABD-F Usage And Synthesis |
| Chemical Properties | Light Yellow Solid | | Uses | Highly reactive fluorogenic reagent for the labeling of thiols for HPLC. ABD-F is nonfluorescent until reacted with thiols and therefore can be used to quantitate thiols in solution, as well as thiols separated by HPLC or TLC. | | Uses | A water soluble pH dependent bifunctional fluorogenic reagent for the sensitive and specific detection of protein thiols. ABD-F is highly reactive and specific for protein thiols, and its selectivity is superior to that of other sulfhydryl-reactive fluorophores such as fluorescein maleimide, 5-iodoacetamidofluorescein, 5-I-AEDANS, dansylaziridine, and bimane.
Fluorescence: max Abs. l = 385nm, max Em. l = 520nm; Molar Abs. > 4.5x103 (ca. 315nm) | | Uses | Reagent for fluorimetric assay of thiols. | | General Description | 4-Fluoro-7-sulfamoylbenzofurazan is a fluorescent reagent, which directly links to the sulfur atom of thiols without a flexible alkyl chain. It is used to detect low molecular thiols using high performance liquid chromatography. |
| | ABD-F Preparation Products And Raw materials |
|
