3-((Dimethylamino)propyl)triphenylphosphonium bromide

3-((Dimethylamino)propyl)triphenylphosphonium bromide Basic information
Product Name:3-((Dimethylamino)propyl)triphenylphosphonium bromide
Synonyms:(3-BROMIDEPROPYL)TRIPHENYLPHOS-PHONIUM BROMIDE, 98+%;(3-Dimethylamino)propyltriphenylphosphonium bromide;(3-(DiMethylaMino)propyl)triphenylphosphoniuM broMide;(3-(Dimethylamino)propyl)triphenylphosphonium bromide 98%;(3-(Dimethylamino);Olopatadine Impurity 19;Olopatadine int;(3-(DiMethylaMino)propyl)triphenylphosphoniuM broMide(3-(DiMethylaMino)propyl)triphenylphosphoniuM broMide
CAS:18355-96-9
MF:C23H27BrNP
MW:428.35
EINECS:605-998-7
Product Categories:C-C Bond Formation;Olefination;Wittig Reagents
Mol File:18355-96-9.mol
3-((Dimethylamino)propyl)triphenylphosphonium bromide Structure
3-((Dimethylamino)propyl)triphenylphosphonium bromide Chemical Properties
Melting point 193-196 °C
storage temp. Inert atmosphere,Room Temperature
BRN 4637548
InChIKeySSWPSKSQQSJKKF-UHFFFAOYSA-M
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
MSDS Information
3-((Dimethylamino)propyl)triphenylphosphonium bromide Usage And Synthesis
Uses(3-(Dimethylamino)propyl)triphenyl-phosphonium Bromide is used in preparation of olopatadine hydrochloride.
UsesReactant for preparation of:
  • Topoisomerase I-targeting antitumor agents
  • C15-C21 stereopentad of discodermolide via cleavage of aminoglycosides, double-bond isomerization, and selective hydroxyl group protection
  • Diphenyl amine based sodium channel blockers, effective against hNav1.2

  • Reactant for Wittig reaction with benzaldehyde
3-((Dimethylamino)propyl)triphenylphosphonium bromide Preparation Products And Raw materials
Olopatadine Impurity 9 1-Propanamine, 3-(diphenylphosphinyl)-N,N-dimethyl- N-DesMethyl Olopatadine [4-(2-Formylbenzyloxy)-3-iodophenyl]acetic Acid Methyl Ester (3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE Olopatadine-d3 N-Oxide HVRLZEKDTUEKQH-NEGCSKJWSA-N Olopatadine Impurity 5 Olopatadine Impurity 11 HBr [3-(ETHOXYCARBONYL)PROPYL]TRIPHENYLPHOSPHONIUM BROMIDE (3-BROMOPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE [3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide 3-((Dimethylamino)propyl)triphenylphosphonium bromide Phosphonium,[(3'S)-1'-[(1,1-dimethylethoxy)carbonyl]-2-oxo[1,3'-bipyrrolidin]-3-yl]triphenyl-,bromide Propyltriphenylphosphonium bromide DIPHENYL-N-PROPYLPHOSPHINE (FORMYLMETHYLENE)TRIPHENYLPHOSPHORANE (3-AMINOPROPYL)DIPHENYLPHOSPHINE

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