2-Ethylaniline

2-Ethylaniline Basic information
Product Name:2-Ethylaniline
Synonyms:2-Ethylbenzeneamine;2-Ethylphenylamine;2-ETHYLANILIN, 1 ML;2-Ethylaniline,98%;Aniline, 2-ethyl-;Aniline, o-ethyl-;Benzenamine, 2-ethyl-;o-ethyl-anilin
CAS:578-54-1
MF:C8H11N
MW:121.18
EINECS:209-424-2
Product Categories:C8;Nitrogen Compounds;Amines
Mol File:578-54-1.mol
2-Ethylaniline Structure
2-Ethylaniline Chemical Properties
Melting point -44 °C (lit.)
Boiling point 210 °C (lit.)
density 0.983 g/mL at 25 °C (lit.)
vapor density 4.2 (vs air)
vapor pressure 0.11 mm Hg ( 20 °C)
refractive index n20/D 1.559(lit.)
Fp 196 °F
storage temp. −20°C
solubility Chloroform (Slightly), Methanol (Slightly)
pkapK1:4.42(+1) (25°C)
form Liquid
color Clear yellow to red-brownish
Water Solubility insoluble
BRN 1841268
InChIKeyMLPVBIWIRCKMJV-UHFFFAOYSA-N
LogP1.74
CAS DataBase Reference578-54-1(CAS DataBase Reference)
NIST Chemistry Reference2-Ethylaniline(578-54-1)
EPA Substance Registry Systemo-Ethylaniline (578-54-1)
Safety Information
Hazard Codes T
Risk Statements 36/37/38-33-23/24/25
Safety Statements 36/37/39-45-36/37-28A
RIDADR UN 2273 6.1/PG 3
WGK Germany 3
RTECS BX9800000
8
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29214980
Hazardous Substances Data578-54-1(Hazardous Substances Data)
MSDS Information
ProviderLanguage
2-Ethylbenzenamine English
SigmaAldrich English
ACROS English
ALFA English
2-Ethylaniline Usage And Synthesis
Chemical Propertiesclear yellow to red-brownish liquid
Chemical Properties2-Ethylaniline is a yellow liquid that turns brown on standing in air
UsesIntermediate for pharmaceuticals, dyestuffs, pesticides, and other products.
Uses2-?Ethylaniline is a reagent in the synthesis of bromoanthraquinones with different substituents producing novel dyes. Also used in the optimization of phoephoinositide 3-kinase inhibitor which is used in the synthesis.
Synthesis Reference(s)The Journal of Organic Chemistry, 45, p. 4926, 1980 DOI: 10.1021/jo01312a021
General DescriptionA brown liquid. Insoluble in water and less dense than water. Hence floats on water. Flash point 185°F. May irritate skin, eyes and mucous membranes. Toxic by ingestion, inhalation or skin absorption.
Air & Water ReactionsInsoluble in water.
Reactivity Profile2-Ethylaniline neutralizes acids in exothermic reactions to form salts plus water. May react with acids to release toxic fumes of aniline and oxides of nitrogen. Reacts violently with oxidizing materials. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Health HazardTOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire HazardCombustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
Flammability and ExplosibilityNotclassified
Safety Profile: A poison. Moderately toxic by ingestion. Flammable when exposed to heat or flame; can react with oxidizing materials. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits highly toxic fumes of aniline and NOx. See also NETHYLANILINE.
Potential ExposureThis material is used in making drugs, dyes, and pesticides.
ShippingUN2273 2-Ethylaniline, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
IncompatibilitiesCombustible; vapor may form explosive mixture with air above 80℃. Decomposes on contact with light or air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, anhydrides, and chloroformates. Contact with metals may evolve flammable hydrogen gas.
3-Anilinopropionitrile 2-Ethylaniline ALTRENOGEST Glycine Ethyl cellulose 2,6-Diethylaniline Hydroxyethyl Cellulose Hydroxyethyl starch 3-Ethylanilinopropiononitrile N-Ethylaniline 2-Fluoroaniline o-Toluidine POLYANILINE O-Tolidine Diphenylamine Tris(hydroxymethyl)aminomethane AMINO ACIDS 3-Aminophenol

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