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| | Phenol Red Basic information |
| | Phenol Red Chemical Properties |
| Melting point | >300 °C | | Boiling point | >300°C | | density | 1.445 Mg m-3 | | refractive index | 1.5300 (estimate) | | Fp | >300°C | | storage temp. | no restrictions. | | solubility | 1 M NaOH: soluble1mg/mL | | form | Solid | | pka | 7.9(at 25℃) | | color | Red | | PH | 6.8～8.4 | | Odor | Odorless | | PH Range | 6.6(YELLOW)-8.0(RED) | | Water Solubility | 0.77 g/L | | λmax | 557nm, 558nm, 360nm, 423nm, 433nm | | Merck | 14,7247 | | BRN | 326470 | | Major Application | Display device, sol-gel matrix, photoreceptors, fuel cells, waveguides, paints, detergents, cosmetics, antiperspirant composition, diapers, screening bacteria, detecting viable cells, diagnosis of urogenital ureaplasmosis, treatment of pathogen infections, amyloid-associated diseases, glaucoma, pulmonary hypertension, asthma, chronic obstructive pulmonary disease, erectile dysfunction, Raynaud’s syndrome, heparin overdose, vulvodynia, wound healing, psychoactive drugs, evaluating dental caries activity | | InChIKey | BELBBZDIHDAJOR-UHFFFAOYSA-N | | LogP | 3.020 | | CAS DataBase Reference | 143-74-8(CAS DataBase Reference) | | EPA Substance Registry System | Phenol Red (143-74-8) |
| | Phenol Red Usage And Synthesis |
| Description | Phenol red belongs to the class of triphenylmethane dyes and is widely used in the textile industry. | | Chemical Properties | dark red powder | | Uses | As indicator in 0.02-0.05% alcohol solution. pH 6.8 yellow, 8.4 red. | | Uses | Phenol red is used as a non absorbed marker in gravimetric method. It is a pH indicator used in cell biology laboratories and in home swimming pool test kits. It is used to check the kidney function based on the excreted phenol red by colorimetric method. | | Uses | Phenol red solution acts as a pH indicator for the culture medium. | | Definition | ChEBI: 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups. A pH indicator changing colour from yellow below pH 6.8 to bright pink above pH 8.2, it is commonly used as an
indicator in cell cultures and in home swimming pool test kits. It is also used in the (now infrequently performed) phenolsulfonphthalein (PSP) test for estimation of overall blood flow through the kidney. | | Application | Phenol red solution has been used:
As a tracer dye for microinjection of zebrafish eggs.
As a component of the mMW medium for preparation of mouse embryos.
In the preparation of versene-ethylenediamine tetraacetic acid (EDTA) solution. | | Preparation | Phenol red is prepared in Dulbecco′s Phosphate Buffered Saline. | | Biochem/physiol Actions | Phenol Red is a pH indicator which changes color from yellow to red. | | Safety Profile | Moderately toxic by ingestion and intravenous routes. Mutation data reported. When heated to decomposition it emits toxicvapors of SOx. | | Enzyme inhibitor | This pH-indicating dye (FW = 354.38 g/mol; CAS 143-74-8; pKa = 7.9; yellow < pH 6.8; red > pH 8.4), also known as phenolsulfonphthalein and sulfophthalein, is a diagnostic aid for evaluating renal function. A typical stock indicator solution is 0.1 g phenol red in 28.2 mL 10 mM NaOH and 221.8 mL water. Target(s): aldehyde reductase; glutaminase; gglutamyl transpeptidase; glutathione S-transferase; 4- methyleneglutaminase; phosphate uptake; thromboxane A2/prostaglandin H2 receptor; and thyroglobulin iodination. |
| | Phenol Red Preparation Products And Raw materials |
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