3-Pyridinesulfonic acid

3-Pyridinesulfonic acid Basic information
Product Name:3-Pyridinesulfonic acid
Synonyms:3-sulfopyridine;PYRIDINE-3-SULPHONIC ACID;PYRIDINE-3-SULFONIC ACID;3-pyridylsulfonicacid;Pyridinesulfonic aci;3-Pyridinesulfonic acid >=98.0% (T);Pyridine-3-sulfonic acid for synthesis;Vonoprazan Fumarate impurity O
CAS:636-73-7
MF:C5H5NO3S
MW:159.16
EINECS:211-265-9
Product Categories:Pyridines, Pyrimidines, Purines and Pteredines;Pyridine;Organic acids;Heterocycle-Pyridine series;bc0001;636-73-7
Mol File:636-73-7.mol
3-Pyridinesulfonic acid Structure
3-Pyridinesulfonic acid Chemical Properties
Melting point >300 °C (lit.)
density 1.7130
refractive index 1.5480 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Crystalline Powder
pka-2.30±0.18(Predicted)
color White to almost white
Water Solubility soluble
Sensitive Light Sensitive
λmax262nm(EtOH aq.)(lit.)
BRN 120822
InChIKeyDVECLMOWYVDJRM-UHFFFAOYSA-N
CAS DataBase Reference636-73-7(CAS DataBase Reference)
Safety Information
Hazard Codes C
Risk Statements 34-22
Safety Statements 26-36/37/39-45-27
RIDADR UN 2585 8/PG 3
WGK Germany 3
RTECS UT7920000
HazardClass 8
PackingGroup III
HS Code 29333999
MSDS Information
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3-Pyridinesulfonic acid English
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3-Pyridinesulfonic acid Usage And Synthesis
Chemical Propertieswhite to almost white crystalline powder
Uses3-Pyridinesulfonic acid can be used in the synthesis of reaction intermediates, such as silver 3-pyridinesulfonate and 3-pyridinesulfonyl chloride.
Purification MethodsPurify the acid by recrystallisation from H2O or aqueous EtOH as needles or plates. [pKa: Evans & Brown J Org Chem 27 3127 1962, IR: Arnett & Chawla J Am Chem Soc 100 214 1978.] UV in 50% aqueous EtOH has at 208 and 262nm. The ammonium salt max has m 243o (from H2O), the sulfonyl chloride has m 133-134o (from pet ether), the amide has m 110-111o (from H2O), the hydrochloride has m >300o(dec), and the N-methyl betaine has m 130o (from H2O). [Gastel & Wibaut Recl Trav Chim Pays-Bas 53 1031 1934, McIlvain & Goese J Am Chem Soc 65 2233 1943, Machek Monatsh Chem 72 77 1938, Beilstein 22 I 616, 22 II 309, 22/7 V 552.]
3-Pyridinesulfonic acid Preparation Products And Raw materials
Raw materialsFUMING SULFURIC ACID-->MERCURY(II) SULFATE
Preparation Products3-Hydroxypyridine-->pyridine-3-sulfonyl chloride-->Pyridine-3-sulfonyl chloride hydrochloride
Hyaluronic acid 4-HYDROXYPYRIDINE-3,5-DISULFONIC ACID 1,3-Propane sultone 2-AMINO-5-PYRIDINESULFONIC ACID,6-Amino-3-pyridinesulfonic Acid p-Toluenesulfonic acid Ethyl 2-(Chlorosulfonyl)acetate 2-Chloro-3-cyanopyridine Taurine 2-(5-chloropyridyl)pyridine-3-sulfonate Ascoric Acid 3-Pyridinesulfonic acid PYRIDINE-3-SULFONIC ACID 1-OXIDE Folic acid 3-Aminopyridine Sulfamic acid Pyridine 5-SULFONICOTINIC ACID Citric acid

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