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N-Acetyl-DL-tryptophan

N-Acetyl-DL-tryptophan Basic information
Product Name:N-Acetyl-DL-tryptophan
Synonyms:DL-alpha-Acetylamino-3-indolepropionic acid;DL-N-Acetyltryptophan;DL-Tryptophan, N-acetyl-;n-acetyl-dl-tryptopha;N-Acetyl-dl-tryptophane;Tryptophan, N-acetyl-, DL-;N-Ac-DL-Trp-OH;Acetyltryptophan Ac-DL-Trp-OH
CAS:87-32-1
MF:C13H14N2O3
MW:246.26
EINECS:201-739-3
Product Categories:amino;amino acid;Amino Acid Derivatives;Amino AcidsBiochemicals and Reagents;Core Bioreagents;Research Essentials;Amino Acids Derivatives;Indoles and derivatives;Tryptophan [Trp, W];Amino Acids and Derivatives;N-Acetyl-Amino acid series;Peptide Synthesis;Tryptophan;Amino Acids;Ac-Amino Acids;Amino Acids;Amino Acids (N-Protected);Biochemistry;Indoles;Tryptophans
Mol File:87-32-1.mol
N-Acetyl-DL-tryptophan Structure
N-Acetyl-DL-tryptophan Chemical Properties
Melting point 204-206 °C (dec.) (lit.)
alpha -0.5～+0.5°(20℃/D)(c=2,C2H5OH)
Boiling point 389.26°C (rough estimate)
density 1.1855 (rough estimate)
refractive index 1.6450 (estimate)
storage temp. 2-8°C
solubility Slightly soluble in water, very soluble in ethanol (96 per cent). It dissolves in dilute solutions of alkali hydroxides.
pka3.65±0.10(Predicted)
form Powder
color White to light yellow
Water Solubility INSOLUBLE IN COLD WATER
BRN 89478
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyDZTHIGRZJZPRDV-UHFFFAOYSA-N
LogP-0.408 (est)
CAS DataBase Reference87-32-1(CAS DataBase Reference)
NIST Chemistry ReferenceAcetyl-dl-tryptophan(87-32-1)
EPA Substance Registry SystemTryptophan, N-acetyl- (87-32-1)
Safety Information
Safety Statements 24/25
WGK Germany 3
Hazard Note Keep Cold
TSCA Yes
HS Code 29339990
MSDS Information
ProviderLanguage
Acetyltryptophan English
ACROS English
SigmaAldrich English
ALFA English
N-Acetyl-DL-tryptophan Usage And Synthesis
Chemical Propertieswhite powder
UsesN-Acetyl-DL-tryptophan is produced via chemical synthesis using the standard amino acid, tryptophan. It can be used in downstream applications of biopharmaceutical production as a transfer agent or stabilizer.
DefinitionChEBI: An N-acetylamino acid that is the N-acetyl derivative of tryptophan.
Flammability and ExplosibilityNotclassified
Purification MethodsA likely impurity is tryptophan. Crystallise it from EtOH by adding water. [Cowgill Biochim Biophys Acta 200 18 1970, DL: Berg J Biol Chem 100 79 1933, Beilstein 22/14 V 40-50.]
N-Acetyl-DL-tryptophan Preparation Products And Raw materials
Preparation Products7-BENZYLOXY-D,L-TRYPTOPHAN
N-Acetyl-L-tryptophan 3-(2-FURYL)ACRYLOYL-L-TRYPTOPHAN METHYL ESTER N-Acetyl-L-cysteine Acetylacetone H-HIS-TRP-OH N-[(tert-Butoxy)carbonyl]-D-tryptophan L-Tryptophan AC-TRP-ONP N-Acetyl-DL-tryptophan Z-ALA-TRP-OH Acetyl chloride H-MET-TRP-OH DL-Tryptophan GLYCYL-DL-TRYPTOPHAN H-LEU-TRP-OH Z-HIS-PHE-TRP-OET L-5-Hydroxytryptophan BZ-TRP-OH
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