NARASIN

NARASIN Basic information
Product Name:NARASIN
Synonyms:monteban;narasina;narasin from streptomyces auriofaciens;Narasia A;Salinomycin, 4-methyl-, (4S)-;(4S)-4-Methylsalinomycin;(4S)-4β-Methylsalinomycin;Narasin (125 mg)
CAS:55134-13-9
MF:C43H72O11
MW:765.03
EINECS:213-574-4
Product Categories:Chiral Reagents;Heterocycles;Antibacterial;Antibiotics;Intermediates & Fine Chemicals;Pharmaceuticals;Antibiotics A to;Antibiotics N-SAntibiotics;Interferes with Cell Membrane Permeability (Ionophores)Spectrum of Activity;L - Z;Mechanism of Action
Mol File:55134-13-9.mol
NARASIN Structure
NARASIN Chemical Properties
Melting point 98-100°
alpha D25 -54° (c = 0.2 in methanol)
Boiling point 842.5±65.0 °C(Predicted)
density 1.17±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility methanol: soluble20mg/mL
pka7.9 (80% aq DMF)
form solution
Safety Information
Hazard Codes T+
Risk Statements 28
Safety Statements 28-36/37-45
RIDADR UN 2811 6.1/PG 2
WGK Germany 3
RTECS VO8640000
HazardClass 6.1(a)
PackingGroup II
HS Code 2941906000
ToxicityLD50 i.p. in mice: 7.15 mg/kg (Berg)
MSDS Information
ProviderLanguage
SigmaAldrich English
NARASIN Usage And Synthesis
Chemical PropertiesWhite Solid
UsesNarasin (4-methylsalinomycin) is a polyether antibiotic isolated from Streptomyces aureofaciens in 1978. Although narasin is a close analogue of salinomycin, the metabolites are produced by different species and are not co-metabolites. Narasin shows broad spectrum activity against Gram positive bacteria including anaerobes and mycoplasma, and also possesses antiviral and limited antifungal activity. Narasin is used in the animal health industry as an in-feed antibiotic and growth promotant.
UsesNarasin is the main component of a polyether antibiotic complex produced by Streptomyces auriofaciens NRRL 5758 & NRRL 8092. Ionophoric antibiotic which inhibits coccidial infection in poultry and mammals. Coccidiostat; growth stimulant.
DefinitionChEBI: Narasin is a diterpene glycoside.
Brand nameMonteban (Lilly).
NARASIN Preparation Products And Raw materials
cis-2,5-Bishydroxymethyl-tetrahydrofuran SERRICORNIN cis-9-Tricosene Acrolein diethyl acetal (3S,5S)-2,6-Dimethyl-3,5-heptanediol 1-(2-METHOXYETHOXY)-2-METHYL-2-PROPANOL DIPENTOXYETHANE ACETALDEHYDE DI-N-HEXYL ACETAL NARASIN (Z)-14-METHYL-8-HEXADECEN-1-AL 2-hydroxyphytanic acid 4-OXATETRADECANOIC ACID CIS-2-METHYL-7-OCTADECENE 4,4-DIMETHOXY-1-BUTENE (Tetrahydro-pyran-2-yl)acetic acid 3-Hydroxytetradecanoic Acid 3-HYDROXYOCTADECANOIC ACID 4-ISOBUTOXY-2-BUTANONE

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