ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Pyridine derivatives 2-Chloro-4-methoxypyridine

2-Chloro-4-methoxypyridine

2-Chloro-4-methoxypyridine Basic information
Product Name:2-Chloro-4-methoxypyridine
Synonyms:IFLAB-BB F1957-0003;2-Chloro-4-methoxypyridine(RS20006968);2-Chloro-4-Methoxypyridine 97%;2-CHLORO-4-METHOXYPYRIDINE;Pyridine,2-chloro-4-Methoxy-;2-chloro-Methoxypyridine;JRH-09202, 2-Chloro-4-methoxypyridine, 97%;2-Chloro-4-methoxypyridine>
CAS:17228-69-2
MF:C6H6ClNO
MW:143.57
EINECS:625-435-9
Product Categories:Heterocycle-Pyridine series;blocks;Pyridines;Pyridine;C6Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks
Mol File:17228-69-2.mol
2-Chloro-4-methoxypyridine Structure
2-Chloro-4-methoxypyridine Chemical Properties
Boiling point 224-225 °C (lit.)
density 1.258 g/mL at 25 °C (lit.)
refractive index n20/D 1.5400(lit.)
Fp >230 °F
storage temp. Inert atmosphere,Room Temperature
solubility Soluble in alcohol.
form Liquid
pka2.25±0.10(Predicted)
Specific Gravity1.258
color Colorless to pale yellow
BRN 1423379
InChIKeyPMTPFBWHUOWTNN-UHFFFAOYSA-N
CAS DataBase Reference17228-69-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37
RIDADR 2810
WGK Germany 3
PackingGroup III
HS Code 29333990
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
2-Chloro-4-methoxypyridine Usage And Synthesis
Chemical PropertiesColorless liquid
UsesIt is an active pharmaceutical ingredient.
Uses2-Chloro-4-methoxypyridine may be used to synthesize:
  • 2-(2′,4′-difluorophenyl)-4-methoxypyridine
  • (2-chloro-4-methoxypyridin-3-yl)bis-[2-(methylsulfanyl)pyrimidin-4-yl]methanol
  • (2-chloro-4-methoxypyridin-3-yl)bis-[2-(methylsulfanyl) pyrimidin-4-yl]methyl acetate
General Description2-Chloro-4-methoxypyridine can be obtained from the reaction between 2-chloro-4-nitropyridine and sodium methoxide in the presence of dioxane. It can also be prepared starting from 4-methoxy-2(1H)-pyridone and 4-nitropyridine N-oxide.
2-Chloro-4-methoxypyridine Preparation Products And Raw materials
Preparation Products2-Chloro-4-hydroxypyridine-->5-BROMO-2-CHLORO-4-METHOXYPYRIDINE
2-CHLORO-4-(2,2,2-TRIFLUORO-ETHOXY)-PYRIDINE 2-Chloro-5-chloromethylpyridine 2-CHLORO-3,4-DIMETHOXYPYRIDINE HYDROCHLORIDE 4-Methoxybenzylchloride 2-Chloro-4-methoxypyridine 5-CHLORO-3-(2-CHLOROETHYL)-7-METHYL-2H-PYRANO[3,2-C]PYRIDIN-2-ONE 2-CHLORO-4-ETHOXYPYRIDINE 6-Chloro-4-ethoxypyridine-3-carboxylic acid ethyl ester SPECS AC-907/25004653 Difluorochloromethane 2-CHLORO-6-METHOXYPYRIDINE,6-Chloro-2-methoxypyridine,2-Chloro-6-methoxypyridine, GC 98% 2,6-DICHLORO-4-METHOXY-PYRIDINE 2-CHLORO-4-METHOXYNICOTINONITRILE Clopidol 2-Chloro-4-picoline 4-Methoxypyridine 6-CHLORO-4-METHOXY-PYRIDINE-2-CARBONITRILE 2-CHLORO-4-ETHOXYNICOTINONITRILE
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