L(+)-2-Aminobutyric acid

L(+)-2-Aminobutyric acid Basic information
Product Name:L(+)-2-Aminobutyric acid
Synonyms:L-2-AMINO-N-BUTYRIC ACID;L-2-AMINOBUTANOIC ACID;L-(+)-2-AMINOBUTYRIC ACID;L-2-AMINOBUTYRIC ACID;L-ABU;L-ALPHA-AMINO-N-BUTYRIC ACID;L-ALPHA-AMINOBUTYRIC ACID;H-ABU-OH
CAS:1492-24-6
MF:C4H9NO2
MW:103.12
EINECS:216-083-3
Product Categories:Amino Acids 13C, 2H, 15N;Amino Acids & Derivatives;Unusual Amino Acids;Chiral Reagents;amino acid;Odevixibat;bc0001
Mol File:1492-24-6.mol
L(+)-2-Aminobutyric acid Structure
L(+)-2-Aminobutyric acid Chemical Properties
Melting point 300 °C
alpha 21.6 º (c=2, 5N HCl)
Boiling point 215.2±23.0 °C(Predicted)
density 1.2300 (estimate)
refractive index 1.4650 (estimate)
storage temp. room temp
solubility 22.7 g/100 mL (22°C)
pka2.29(at 25℃)
form Crystalline Powder
color White to beige
Water Solubility 22.7 g/100 mL (22 ºC)
Merck 14,428
BRN 1720935
InChIKeyQWCKQJZIFLGMSD-VKHMYHEASA-N
CAS DataBase Reference1492-24-6(CAS DataBase Reference)
NIST Chemistry Reference(l)-2-Aminobutanoic acid(1492-24-6)
EPA Substance Registry SystemButanoic acid, 2-amino-, (2S)- (1492-24-6)
Safety Information
Hazard Codes Xi
Risk Statements 43
Safety Statements 36/37
WGK Germany 3
Hazard Note Irritant
TSCA Yes
HS Code 29224999
MSDS Information
ProviderLanguage
L-2-Aminobutanoic acid English
SigmaAldrich English
ACROS English
ALFA English
L(+)-2-Aminobutyric acid Usage And Synthesis
Chemical PropertiesWhite Crystalline Solid
Usesaminobutyric acid is an amino acid with water-binding properties and possible anti-inflammatory capacities.
UsesL-(+)-2-Aminobutyric acid is used in the biosynthesis of nonribosomal peptides. It acts as a receptor antagonist. It is also used as a chiral reagent. Further, it is used in the determination of substrate of glutamyl cysteine acid synthase. In addition to this, it is also utilized as a drug intermediate.
DefinitionChEBI: An optically active form of alpha-aminobutyric acid having L-configuration.
Synthesis Reference(s)Journal of the American Chemical Society, 68, p. 450, 1946 DOI: 10.1021/ja01207a032
General DescriptionL-2-Aminobutyric acid is synthesized from L-threonine and L-aspartic acid through a ?-transamination reaction. It is an L-alanine analogue with an ethyl side chain.
Biochem/physiol ActionsL-α-Aminobutyric acid (AABA) is an isomer of the non-natural amino acid aminobutyric acid with activity in the γ-glutamyl cycle that regulates glutathione biosynthesis. Recently AABA has been studied as a supplement to in vitro maturation medium (NCSU 23 medium) for culture of oozytes and embryos. This product has been qualified for use in cell culture. AABA is also used as a substitute amino acid for alanine in studies on peptide function.
Purification MethodsCrystallise butyrine from aqueous EtOH, and the melting point depends on heating rate but has m 303o in a sealed tube. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 2399 IR: 2401 1961, Beilstein 4 III 1294, 4 IV 2584.]
L(+)-2-Aminobutyric acid Preparation Products And Raw materials
Preparation ProductsBOC-ABU-OH-->(R)-(-)-2-Aminobutane
Hydrocortisone-17-butyrate D-2-Aminobutyric acid Ethyl 2-(Chlorosulfonyl)acetate 4-Aminobutyric acid Liothyronine sodium Ascoric Acid Ethyl N-acetyl-L-tyrosinate hydrate L(+)-2-Aminobutyric acid O-PHOSPHO-L-TYROSINE N-ALPHA-BENZOYL-L-ARGININE O-METHYL-D-TYROSINE Folic acid Ethyl N-benzoyl-L-tyrosinate L-Thyroxine Methyl L-tyrosinate Cycloleucine DL-2-AMINOBUTYRIC ACID r-Amino Butryric Acid Aminobutyric Acid

Email:[email protected] [email protected]
Copyright © 2025 Mywellwork.com All rights reserved.