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| | Ginsenoside Rh2 Basic information |
| Product Name: | Ginsenoside Rh2 | | Synonyms: | b-D-Glucopyranoside, (3b,12b)-12,20-dihydroxydaMMar-24-en-3-yl;(3β,12β)-12,20-Dihydroxydammar-24-en-3-yl-β-D-glucopyranoside;Ginsenoside Rh2, 20(S)-;(3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl beta-d-glucopyranoside;GINSENOSIDE RH2;dihydroxydammar-24-en-3-yl;β-D-Glucopyranoside, (3β,12β)-12,20-;R-form-Ginsenoside Rh2 | | CAS: | 78214-33-2 | | MF: | C36H62O8 | | MW: | 622.88 | | EINECS: | | | Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors;Ginsenoside series;78214-33-2 | | Mol File: | 78214-33-2.mol |  |
| | Ginsenoside Rh2 Chemical Properties |
| Melting point | 139-144 °C | | Boiling point | 726.4±60.0 °C(Predicted) | | density | 1.19±0.1 g/cm3(Predicted) | | storage temp. | Inert atmosphere,2-8°C | | solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml | | form | neat | | pka | 12.91±0.70(Predicted) | | color | White | | InChIKey | CKUVNOCSBYYHIS-IRFFNABBSA-N | | LogP | 5.620 (est) | | CAS DataBase Reference | 78214-33-2(CAS DataBase Reference) |
| Hazard Codes | Xn | | Risk Statements | 22 | | Safety Statements | 24/25 | | WGK Germany | 3 | | RTECS | LZ5776539 | | HS Code | 29389090 |
| | Ginsenoside Rh2 Usage And Synthesis |
| Description | Ginsenoside Rh2 is a steroid glycoside found in plants of the genus Panax that has diverse biological activities. It inhibits release of β-hexosaminidase from RBL-2H3 cells (IC50 = 100 μM) and inhibits the IgE-dependent passive cutaneous anaphylaxis reaction in mice at a dose of 25 mg/kg. It inhibits growth of HRA ovarian and BxPC-3 pancreatic cancer cells in a dose-dependent manner. In vivo, ginsenoside Rh2 decreases immobility time in the forced swim test in a mouse model of colorectal carcinoma. Ginsenoside Rh2 also reduces infarct volume in a rat model of ischemia-reperfusion-induced brain injury. | | Chemical Properties | White solid | | Uses | 20(S)-Ginsenoside Rh2 is a bioactive metabolite of the ginsenoside component of Panax ginseng that has been shown to exhibit antibacterial effects in vitro. | | Definition | ChEBI: A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3
has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position. |
| | Ginsenoside Rh2 Preparation Products And Raw materials |
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