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| | Pyrroloquinoline quinone disodium salt Basic information |
| Product Name: | Pyrroloquinoline quinone disodium salt | | Synonyms: | disodium4,5-dihydro-4,5-dioxo-1h-pyrrolo(2,3-f)quinoline-2,7,9-tricarboxylat;PQQ, Pyrrolo-quinoline-quinone disodium salt;sodiuM 9-carboxy-4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7-dicarboxylate;PQQ disodium;1H-Pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylicacid, 4,5-dihydro-4,5-dioxo-, sodium salt;PYRROLOQUINOLINE QUINONE DISODIUM SALTPYRROLOQUINOLINE QUINONE DISODIUM SALT;PQQ Disodium Salt;PYRROLOQUINOLINE QUINONE DISODIUM SALT | | CAS: | 122628-50-6 | | MF: | C14H4N2Na2O8 | | MW: | 374.17 | | EINECS: | 209-118-9 | | Product Categories: | PQQ;122628-50-6 | | Mol File: | 122628-50-6.mol |  |
| | Pyrroloquinoline quinone disodium salt Chemical Properties |
| storage temp. | 2-8°C | | Water Solubility | Water : 6.16 mg/mL (16.46 mM) | | InChI | InChI=1S/C14H6N2O8.Na.H/c17-10-4-2-6(14(23)24)15-8(4)7-3(12(19)20)1-5(13(21)22)16-9(7)11(10)18;;/h1-2,15H,(H,19,20)(H,21,22)(H,23,24);; | | InChIKey | UFVBOGYDCJNLPM-UHFFFAOYSA-L | | SMILES | C(C1C=C(C(=O)O)N=C2C(=O)C(=O)C3C=C(C(=O)O)NC=3C=12)(=O)O.[NaH] |
| WGK Germany | 3 | | RTECS | UY9454762 | | F | 10-21 |
| | Pyrroloquinoline quinone disodium salt Usage And Synthesis |
| Description | Pyrroloquinoline quinone disodium salt is a water-soluble quinone compound that has a strong antioxidant capacity. This product is a reddish-brown colored powder. It is isolated from cultures of methylotrophic bacteria and tissues of mammals. This essential nutrient is vital for mammals, playing a crucial role in enhancing immune function. | | Uses | Pyrroloquinoline quinone disodium salt can act as an antioxidant and there is strong evidence that PQQ may play an important role in important pathways of cell signaling. PQQ plays a variety of physiological roles, such as promoting growth and reproduction and providing neurological and cardiovascular protection. | | Application | Pyrroloquinoline quinone disodium salt protects cells from oxidative damage and increases the mitochondrial membrane potential, which is essential for the production of ATP. It also stimulates enzyme activities, such as glutathione peroxidase and glutathione reductase, and prevents lipid peroxidation of human serum. This compound also inhibits radiation-induced cellular damage by preventing DNA strand breakage. It may be effective in treating diseases related to oxidative stress, such as diabetes and cancer. | | Source | Methoxatin/pyrroloquinoline quinone (PQQ) is mostly seen in plants, few bacteria and single cell eukaryotes, like yeast. It is mainly obtained from methylotrophic bacteria. PQQ may also present in the tissues of mammals. | | Biochem/physiol Actions | In bacteria, pyrroloquinoline quinone (PQQ) is used as a redox cycling cofactor. It acts as a cofactor (prosthetic group) for enzyme-catalyzed redox reactions of glucose and methanol dehydrogenase(s). PQQ is used in liposomes to establish a simple homogeneous assay for the detection of membrane permeabilization by antimicrobial peptides and synthetic copolymers. In bovine plasma amine oxidase, methoxatin may acts as the cofactor. | | Side effects | From Self-Hacked: Anecdotally, some people have reported mild headaches and insomnia – usually either if too much is taken or if someone is very sensitive to the effects of supplements.
From Dr. Axe: The most commonly reported pyrroloquinoline quinone side effects include headaches, drowsiness and fatigue. Extremely high doses can also be dangerous and have actually been associated with some serious and potentially life-threatening effects on health.
keep.health/pqq-pyrroloquinoline-quinone/ |
| | Pyrroloquinoline quinone disodium salt Preparation Products And Raw materials |
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