(-)-ALPHA-BISABOLOL

(-)-ALPHA-BISABOLOL Basic information

Product Name:	(-)-ALPHA-BISABOLOL
Synonyms:	A-(-)-BISABOLOL;CAMILLOL;BISABOLOL, A-(-)-;BISABOLOL OXIDE A;DRAGOSANTOL;HYDAGEN B;LEVOMENOL;theta)]-thet
CAS:	23089-26-1
MF:	C15H26O
MW:	222.37
EINECS:	245-423-3
Product Categories:	Miscellaneous Natural Products
Mol File:	23089-26-1.mol

(-)-ALPHA-BISABOLOL Chemical Properties

alpha	D -55.7°; D20 -51.02° (Günther)
Boiling point	bp12 153°
density	d20 0.9211
vapor pressure	0.015Pa at 20℃
refractive index	n20/D 1.496
FEMA	4666 \| ALPHA-BISABOLOL
Fp	135 °C
storage temp.	-20°C
solubility	DMSO:100.0(Max Conc. mg/mL);449.7(Max Conc. mM)
pka	15.04±0.29(Predicted)
form	neat
Odor	at 100.00 %. fruity nutty coconut
Odor Type	floral
optical activity	[α]/D -60±2°, neat
Water Solubility	22mg/L at 20℃
JECFA Number	2031
LogP	5.5 at 25℃
CAS DataBase Reference	23089-26-1(CAS DataBase Reference)
EPA Substance Registry System	Levomenol (23089-26-1)

Safety Information

RIDADR	UN 3082 9 / PGIII
WGK Germany	3
RTECS	MJ9685000
HS Code	2906195000
Toxicity	LD50 in male, female mice, rats (ml/kg): 15.2, 15.0, 14.9, 15.6 orally (Habersang)

MSDS Information

(-)-ALPHA-BISABOLOL Usage And Synthesis

Uses	(-)-α-Bisabolol was used to investigate the leishmanicidal and cytotoxic activity of essential oil of Vanillosmopsis arborea.
Uses	Reference Standard in the analysis of herbal medicinal products
Definition	ChEBI: (-)-alpha-Bisabolol is a sesquiterpenoid.
General Description	(-)-α-Bisabolol is the major constituent of essential oil from leaves of Hymenocrater yazdianus.
Flammability and Explosibility	Notclassified
Biochem/physiol Actions	α-Bisabolol is active against primary acute leukemia cells, including BCR-ABL(+) acute lymphoblastic leukemias. It is the inhibitor of voltage-dependent Ca(2+) channels in tracheal smooth muscle preparations of rat. It also inhibits human and rat glioma cell growth and survival. It is a potential new therapeutic agent against leishmaniasis.

(-)-ALPHA-BISABOLOL Preparation Products And Raw materials

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