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DESTHIAZOLYLMETHYL RITONAVIR

DESTHIAZOLYLMETHYL RITONAVIR Basic information
Product Name:DESTHIAZOLYLMETHYL RITONAVIR
Synonyms:Ritonavir EP IMP L;(2S)-N-(((1S)-1-benzyl-2-((4S,5S)-4-benzyl-2-oxo-1,3-oxazolidin-5-yl)ethyl)-2-((((2-isopropyl-1,3-thiazol-4-yl)methyl)N-methyl-amino)carbonyl)amino)-3-methylbutanamide;DESTHIAZOLYLMETHYL RITONAVIR;(2S)-3-Methyl-2-[[[Methyl[[2-(1-Methylethyl)-4-thiazolyl]Methyl]aMino]carbonyl]aMino]-N-[(1S)-1-[[(4S,5S)-2-oxo-4-(phenylMethyl)-5-oxazolidinyl]Methyl]-2-phenylethyl]-butanaMide;(S)-N-((S)-1-((4S,5S)-4-benzyl-2-oxooxazolidin-5-yl)-3-phenylpropan-2-yl)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanamide;RitonavirEP ImpurityL;Ritonavir Impurity 12(Ritonavir EP Impurity L);Ritonavir EP Impurity L(BP Impurity L)
CAS:256328-82-2
MF:C33H43N5O4S
MW:605.79
EINECS:
Product Categories:Anti-virals;Inhibitors;Anti-viral Compounds;Intermediates & Fine Chemicals;Non-nucleoside Reverse Transcriptase;Pharmaceuticals;Anti-virals, Inhibitors, Non-nucleoside Reverse Transcriptase, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:256328-82-2.mol
DESTHIAZOLYLMETHYL RITONAVIR Structure
DESTHIAZOLYLMETHYL RITONAVIR Chemical Properties
Melting point 65-69°C
Boiling point 874.0±65.0 °C(Predicted)
density 1.185±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly), DMSO (Slightly, Sonicated), Methanol (Slightly)
pka12.40±0.46(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
DESTHIAZOLYLMETHYL RITONAVIR Usage And Synthesis
Chemical PropertiesFoam
UsesDesthiazolylmethyl Ritonavir (Ritonavir EP Impurity L) is an analogue of the selective HIV protease inhibitor Ritonavir (R535000). It is a COVID19-related research product.
DESTHIAZOLYLMETHYL RITONAVIR Preparation Products And Raw materials
Ritonavir Ritonavir EP Impurity O DESTHIAZOLYLMETHYLOXYCARBONYL RITONAVIR 2,3-Dihydroxypropyl (3S,6S,8S,9S)-8-hydroxy-3-(1-methylethyl)-4,11-dioxo-6,9-bis(phenylmethyl)-13-(5-thiazolyl)-12-oxa-2,5,10-triazatridecanoate Anti Low-density lipoprotein (LDL) 1 mg/200 µ (5S,8S,9S,11S)-9-Hydr Thiazol-5-ylmethyl ((2S,3S,5S)-5-((S)-2-amino-3-methylbutanamido)-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate Ritonavir EP Impurity T Des(isopropylthiazolyl) Hydantoin Ritonavir (3S,4S,6S,9S)-13-[2-(1-Hydroperoxy-1-methylethyl)-4-thiazolyl]-4-hydroxy-12-methyl-9-(1-methylethyl)-8,11-dioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraazatridecanoic Acid 5-thiazolylmethyl Ester N-[N-methyl-N-((2-isopropyl-4-thiazolyl)methyl)amino)carbonyl]-L-valine，Lithium Salt Hydroxy Ritonavir (2S,3S,5S)-5-(tert-Butoxycarbonylamino)-2-(N-5-thiazolylmethoxycarbonyl)amino-1,6-diphenyl-3-hydroxyhexane Ritonavir O-Acyl Isomer (4S,5S)-4-Benzyl-5-[(2S)-2-((4S)-4-isopropyl-2,5-dioxoiMidazolidin-1-yl)-3-phenylpropyl]-2-oxo-1,3-oxazolidine-3-carboxylate thiazol-5-ylMethyl Ester [5S-(5R*,8R*,10R*,11R* N-[(1S,2S,4S)-4-(AcetylaMino)-2-hydroxy-5-phenyl-1-(phenylMethyl)pentyl]carbaMic Acid 5-ThiazolylMethyl Ester (S)-2-(3-((2-Isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoic acid
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