Demethyl tetrandrine

Demethyl tetrandrine Basic information
Uses
Product Name:Demethyl tetrandrine
Synonyms:Demethyl tetrandrine;Hanfangchin B;Thaligine;Thalrugosine;Fangchinoline;Menisidine;Berbaman-7-ol, 6,6',12-trimethoxy-2,2'-dimethyl-;Nsc 277171
CAS:33889-68-8
MF:C37H40N2O6
MW:608.72
EINECS:
Product Categories:Inhibitors;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File:33889-68-8.mol
Demethyl tetrandrine Structure
Demethyl tetrandrine Chemical Properties
Melting point 212-4°C (dec. ).
Boiling point 709.7±60.0 °C(Predicted)
density 1.204±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly)
form Solid
pka9.38±0.20(Predicted)
color Off-White to Pale Beige
Safety Information
MSDS Information
Demethyl tetrandrine Usage And Synthesis
UsesFangchinoline is an isolate from Stephania Tetrandra that shows anti-cancer activity. It inhibits breast adenocarcinoma proliferation through apoptosis induction. In addition, it has been shown to inhibit HIV-Type 1 replication.
DescriptionThalictrum rugosum Ait also contains this alkaloid which is dextrorotatory with [o:lbo + 128° (MeOH). The ultraviolet spectrum of this base consists of a single absorption maximum at 283 flI/J..
UsesFangchinoline is an isolate from Stephania Tetrandra that shows anti-cancer activity. It inhibits breast adenocarcinoma proliferation through apoptosis induction. In addition, it has been shown to inhibit HIV-Type 1 replication.
targetDNA/RNA Synthesis
ReferencesMitscher et al., Chem. Commun., 589 (1971)
Demethyl tetrandrine Preparation Products And Raw materials
Isohomoarbutin Naphth[2,3,-b]oxiren-2(1aH)-one, 4, Isosaponarin 2''-O-glucoside Wogonin 3-PHENOXYPHENETHYLAMINE MAGNOLINE 2,2'-DIHYDROXYDIPHENYL ETHER CHEMBRDG-BB 5209105 3-(1-(Dimethylamino)ethyl]phenol Phenol, 2-[(1R)-1-aminoethyl]- Demethyl tetrandrine SALSOLIDINE 1,2-Benzenediol, 4-(1-aminoethyl)-, (R)- (9CI) 2,2',3-TRIHYDROXYDIPHENYL ETHER ISOTETRANDRINE (S)-1-(3,4-Dimethoxyphenyl)ethylamine N-Methyl-3-phenoxybenzylamine Phenol, 5-(1-aminoethyl)-2-methoxy-, (R)-

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