ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyrimidines Methylpyrimidine ETHYL 2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE

ETHYL 2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE

ETHYL 2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE Basic information
Product Name:ETHYL 2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE
Synonyms:ETHYL 2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE;5-PYRIMIDINECARBOXYLIC ACID, 2-(TRIFLUOROMETHYL)-, ETHYL ESTER;5-(Ethoxycarbonyl)-2-(trifluoromethyl)pyrimidine;Ethyl 2-(trifluoromethyl);ETHYL 2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE ISO 9001：2015 REACH
CAS:304693-64-9
MF:C8H7F3N2O2
MW:220.15
EINECS:
Product Categories:pyrimidine;Fluorine series
Mol File:304693-64-9.mol
ETHYL 2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE Structure
ETHYL 2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE Chemical Properties
Melting point 65 °C
Boiling point 194℃
density 1.344
Fp 71℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form powder
pka-3.50±0.22(Predicted)
color Yellow
Safety Information
HS Code 2933599590
MSDS Information
ETHYL 2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE Usage And Synthesis
UsesEthyl 2-(Trifluoromethyl)pyrimidine-5-carboxylate is used to prepare NF-κB and AP-1 gene inhibitors.
ETHYL 2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE Preparation Products And Raw materials
Raw materialsEthanol-->Ethyl acetate-->Diethyl ether-->Dichloromethane-->Sodium hydride-->Silica gel-->Trifluoroacetamidine-->ETHYL 3,3-DIETHOXYPROPIONATE
ETHYL-2-TRIFLUOROMETHYL-4-(2-FLUOROPHENYL)-5-PYRIMIDINE CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-(2-NITROPHENYL)-5-PYRIMIDINE CARBOXYLATE ETHYL 4-AMINO-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-ISOPROPYL-5-PYRIMIDINE CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-(2-METHYLPHENYL)-5-PYRIMIDINE CARBOXYLATE Ethyl 4-chloro-2-(trifluoromethyl)pyrimidine-5-carboxylate ETHYL 4-HYDROXY-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE ETHYL 4-(2-[(2,6-DICHLORO-4-PYRIDYL)CARBONYL]HYDRAZINO)-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-PROPYL-5-PYRIMIDINE CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-METHYL-5-PYRIMIDINE CARBOXYLATE ETHYL 4-HYDRAZINO-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-(2-IODOPHENYL)-5-PYRIMIDINE CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-ETHYL-5-PYRIMIDINE CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-CYCLOPROPYL-5-PYRIMIDINE CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-(2-CHLOROPHENYL)-5-PYRIMIDINE CARBOXYLATE SODIUM 5-(ETHOXYCARBONYL)-2-(TRIFLUOROMETHYL)PYRIMIDIN-4-OLATE ETHYL-2-TRIFLUOROMETHYL-4-(2-BROMOPHENYL)-5-PYRIMIDINE CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-TRIFLUOROMETHYL-5-PYRIMIDINE CARBOXYLATE
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