ChemicalBook Product Catalog Organic Chemistry Amides Naphthenic amines derivatives 4-TRIFLUOROMETHYL-N-METHYLANILINE 97

4-TRIFLUOROMETHYL-N-METHYLANILINE 97

4-TRIFLUOROMETHYL-N-METHYLANILINE 97 Basic information
Product Name:4-TRIFLUOROMETHYL-N-METHYLANILINE 97
Synonyms:4-(Methylamino)benzotrifluoride;BenzenaMine, N-Methyl-4-(trifluoroMethyl)-;4-(Trifluoromethyl)-N-methylaniline 97%;4-TRIFLUOROMETHYL-N-METHYLANILINE 97;4-(TRIFLUOROMETHYL)-N-METHYLANILINE, 97% MIN.;n-methyl-n-[4-(trifluoromethyl)phenyl]amine;N-Methyl-4-(trifluoromethyl);N-Methyl-p-trifluoromethylaniline
CAS:22864-65-9
MF:C8H8F3N
MW:175.15
EINECS:245-739-1
Product Categories:Phenyls & Phenyl-Het;C8;Nitrogen Compounds;Fluorine series;Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Amines;Phenyls & Phenyl-Het
Mol File:22864-65-9.mol
4-TRIFLUOROMETHYL-N-METHYLANILINE 97 Structure
4-TRIFLUOROMETHYL-N-METHYLANILINE 97 Chemical Properties
Boiling point 105-106 °C/20 mmHg (lit.)
density 1.2394 g/mL at 25 °C (lit.)
refractive index n20/D 1.4888(lit.)
Fp 210 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka2.58±0.12(Predicted)
form clear liquid
color Colorless to Light orange to Yellow
InChIKeyUTUYWZJPVLDHJJ-UHFFFAOYSA-N
Safety Information
Hazard Codes Xn
Risk Statements 22-43
Safety Statements 36/37
WGK Germany 3
HS Code 2921430090
MSDS Information
4-TRIFLUOROMETHYL-N-METHYLANILINE 97 Usage And Synthesis
Uses4-(Trifluoromethyl)-N-methylaniline is used in the synthesis of Tasquinimod (T007820), an orally active antiangiogenic agent which may inhibit HDAC4 signalling. This affects cancer cell survival thus making this compound and anti-cancer agent.
4-TRIFLUOROMETHYL-N-METHYLANILINE 97 Preparation Products And Raw materials
Raw materialsHydrochloric acid-->Sulfuric acid-->Tetrahydrofuran-->Lithium Aluminum Hydride-->Diethylamine-->4-Dimethylaminopyridine-->Ethyl chloroformate-->4-Aminobenzotrifluoride-->Trimethoxymethane
Preparation Productstasquinimod
4-Bromo-2-fluoro-N-methylbenzamide N-methyl-2-bromo-4-fluorobenzamide 4-BroMo-3-fluoro-N-Methylaniline N-Methyl-2-fluoro-4-iodobenzamide 2-FLUORO-N-METHYL-4-NITROBENZAMIDE N,N-BIS(2-PHENYL-ETHYL)-N-METHYL-AMINE N-METHYL-N-PHENYLURETHANE N-METHYL-N-[4-(TRIFLUOROMETHYL)BENZYL]AMINE N-Methyl-4-Nitro-Benzamide N-[4-(TRIFLUOROMETHYL)PHENYL]-4-FLUOROBENZAMIDE 2-(3,4-DIHYDROISOQUINOLIN-2(1H)-YL)-5-(TRIFLUOROMETHYL)ANILINE N-(2-AMINO-4-TRIFLUOROMETHYLPHENYL)PIPERIDINE 1-(4-TRIFLUOROMETHYLPHENYL)PIPERAZINE N-ETHYL 2-NITRO-4-(TRIFLUOROMETHYL)ANILINE 3-AMINO-4-(4-MORPHOLINO)BENZOTRIFLUORIDE BUTTPARK 83\09-87 N-[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]PYRROLIDINE N-(2-AMINO-4-TRIFLUOROMETHYLPHENYL)PYRROLIDINE
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