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| SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Basic information |
Product Name: | SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 | Synonyms: | SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9;3,7,12-trihydroxy-, monosodium salt;3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt;Cholalic acid sodium salt;SODIUM CHOLATE HYDRATE, 98 %;SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 96.0% NT DRY MATTER;SODIUM CHOLATE HYDRATE, CELL CULTURE TESTED;SODIUM CHOLATE HYDRATE, PURUM, >= 97.0% NT DRIED MATERIAL | CAS: | 206986-87-0 | MF: | C24H43NaO6 | MW: | 450.59 | EINECS: | 206-643-5 | Product Categories: | | Mol File: | 206986-87-0.mol | |
| SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Chemical Properties |
RTECS | FZ9600000 | storage temp. | Store at RT. | solubility | H2O: 0.1 M, clear | form | Powder | color | White | optical activity | [α]20/D +36±2°, c = 0.6% in ethanol (dry matter) | Water Solubility | Soluble in water. | BRN | 3582354 |
Safety Statements | 24/25 | WGK Germany | 3 | F | 3-9 | TSCA | Yes | HS Code | 29181990 |
| SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Usage And Synthesis |
Uses | Biochemical solubilizing agent Sodium cholate hydrate is a non-denaturing detergent used for the extraction of membrane proteins. It is involved in the study to assess infiltration of pressurized promoter solutions in a mesoporous silica. Further, it serves as a biochemical solubilizing agent. | Uses | Cholate is a bile acid produced in liver during cholesterol breakdown. Cholate downregulates cholesterol-7-α-hydroxylase (rate-limiting step in bile acid synthesis). Cholate, an anionic detergent, is used alone and in combination with urea to extract and reconstitute membrane proteins and protein complexes. | Uses | Non-denaturing detergent used for extraction of membrane proteins. | General Description | Sodium cholate hydrate is a non-denaturing, anionic detergent. | Biochem/physiol Actions | Reduction in 12-α hydroxylase activity leads to low levels of cholic acid in liver disease. |
| SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Preparation Products And Raw materials |
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