SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9

SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Basic information
Product Name:SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9
Synonyms:SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9;3,7,12-trihydroxy-, monosodium salt;3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt;Cholalic acid sodium salt;SODIUM CHOLATE HYDRATE, 98 %;SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 96.0% NT DRY MATTER;SODIUM CHOLATE HYDRATE, CELL CULTURE TESTED;SODIUM CHOLATE HYDRATE, PURUM, >= 97.0% NT DRIED MATERIAL
CAS:206986-87-0
MF:C24H43NaO6
MW:450.59
EINECS:206-643-5
Product Categories:
Mol File:206986-87-0.mol
SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Structure
SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Chemical Properties
RTECS FZ9600000
storage temp. Store at RT.
solubility H2O: 0.1 M, clear
form Powder
color White
optical activity[α]20/D +36±2°, c = 0.6% in ethanol (dry matter)
Water Solubility Soluble in water.
BRN 3582354
Safety Information
Safety Statements 24/25
WGK Germany 3
3-9
TSCA Yes
HS Code 29181990
MSDS Information
SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Usage And Synthesis
UsesBiochemical solubilizing agent Sodium cholate hydrate is a non-denaturing detergent used for the extraction of membrane proteins. It is involved in the study to assess infiltration of pressurized promoter solutions in a mesoporous silica. Further, it serves as a biochemical solubilizing agent.
UsesCholate is a bile acid produced in liver during cholesterol breakdown. Cholate downregulates cholesterol-7-α-hydroxylase (rate-limiting step in bile acid synthesis). Cholate, an anionic detergent, is used alone and in combination with urea to extract and reconstitute membrane proteins and protein complexes.
UsesNon-denaturing detergent used for extraction of membrane proteins.
General DescriptionSodium cholate hydrate is a non-denaturing, anionic detergent.
Biochem/physiol ActionsReduction in 12-α hydroxylase activity leads to low levels of cholic acid in liver disease.
SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Preparation Products And Raw materials
5-BETA-CHOLANIC ACID-7-ALPHA, 12-ALPHA-DIOL Sodium octanoate sodium docosanoate Sodium cholate LITHOCHOLIC ACID CHOLANIC ACID Sodium deoxycholate STEARATE 5-BETA-CHOLAN-24-OL Sodium stearate LAURIC ACID SODIUM SALT CAPRIC ACID SODIUM SALT 12-HYDROXYDODECANOIC ACID 5BETA-CHOLANIC ACID Sodium Palmitate SODIUMLITHOCHOLATE PELARGONIC ACID SODIUM SALT 2,7-Decahydronaphthalenediol

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