N-BOC-cis-4-fluoro-L-proline

N-BOC-cis-4-fluoro-L-proline Basic information
Product Name:N-BOC-cis-4-fluoro-L-proline
Synonyms:(2S,4S)-4-Fluoropyrrolidine-2-carboxylic acid, N-BOC protected;cis-4-Fluoro-L-proline, N-BOC protected;(2S,4S)-1-Boc-4-fluoro-2-pyrrolidinecarboxylic Acid N-(tert-Butoxycarbonyl)-cis-4-fluoro-L-proline N-Boc-cis-4-fluoro-L-proline;Boc-(2S,4S)-4-fluoro-pyrrolidine-2-carboxylic acid, Boc-flp-OH;Boc-4-F-L-Pro-OH;cis-4-Fluoro-L-proline, N-BOC protected, (4S)-1-(tert-Butoxycarbonyl)-4-fluoro-L-proline;(2S,4S)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid;Boc-cis-4-F-L-Pro-OH
CAS:203866-13-1
MF:C10H16FNO4
MW:233.24
EINECS:
Product Categories:Carboxylic Acids (Chiral);Chiral Building Blocks;Synthetic Organic Chemistry;Chiral Building Blocks;Heterocyclic Building Blocks;Pyrrolidines;Nitrogen cyclic compounds;11
Mol File:203866-13-1.mol
N-BOC-cis-4-fluoro-L-proline Structure
N-BOC-cis-4-fluoro-L-proline Chemical Properties
Melting point 157-161.°C
Boiling point 346.0±42.0 °C(Predicted)
density 1.24±0.1 g/cm3(Predicted)
refractive index -57 ° (C=1, MeOH)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka3.53±0.40(Predicted)
form powder to crystal
color White to Almost white
optical activity[α]22/D 71.0±5°, c = 1 in chloroform
InChIKeyYGWZXQOYEBWUTH-BQBZGAKWSA-N
CAS DataBase Reference203866-13-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
WGK Germany 3
HazardClass IRRITANT
HS Code 29339900
MSDS Information
N-BOC-cis-4-fluoro-L-proline Usage And Synthesis
Chemical PropertiesWhite powder
UsesN-Boc-cis-4-fluoro-L-proline can be used as a substrate in the preparation of:
  • α4β2 Receptor ligands bearing pyrrolidine nucleus.
  • β-Amino pyrrolidine-2-carbonitrile derivatives as possible dipeptidyl peptidase IV (DPP4) inhibitors.

N-Boc-(2R,3R,4S)-dolaproine TERT-BUTYL N-(2-HYDROXYETHYL)CARBAMATE N-Boc-endo-3-aminotropane N-Boc-exo-3-aminotropane N-Boc-3-piperidineacetic acid N-Boc-L-trans-4,5-Methanoproline N-Boc-O-tosyl hydroxylamine N-BOC-6-azaspiro[3.4]octan-2-ol Fluorine BOC-4,4-DIFLUORO-L-PROLINE METHYL ESTER Ascoric Acid METHYL-2-PYRROLIDONE CARBOXYLIC ACID BOC-CIS-4-FLUORO-5-OXO-L-PROLINE METHYL ESTER L-PROLINE-(4-3H(N)) (2S,4S)-1-tert-butyl 2-methyl 4-fluoropyrrolidine-1,2-dicarboxylate tert-Butyl carbazate N-Boc-cis-4-Fluoro-D-Proline

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