Enantioselective alkylation of malonic diester with alkyl halides
Hydrolysis of enol esters
Asymmetric 6π electrocyclization for synthesis of functionalized indolines
Asymmetric Michael addition
Alkylation of monosubstituted indolinones with alkylhalides
Asymmetric destruction and kinetic resolution of 1-benzylated Reissert compounds
Purification Methods
Recrystallise the chloride from isoPrOH, toluene or small volumes of H2O. It is a good chiral phase transfer catalyst [Julia et al. J Chem Soc, Perkin Trans 1 574 1981, Hughes et al. J Am Chem Soc 106 446 1984, Hughes et al. J Org Chem 52 4745 1987].
N-BENZYLCINCHONINIUM CHLORIDE Preparation Products And Raw materials
