ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Pyridine derivatives 1H-PYRROLO[2,3-B]PYRIDIN-5-OL

1H-PYRROLO[2,3-B]PYRIDIN-5-OL

1H-PYRROLO[2,3-B]PYRIDIN-5-OL Basic information
Product Name:1H-PYRROLO[2,3-B]PYRIDIN-5-OL
Synonyms:5-Hydroxy-7-azaindole 97%;5-hydroxypyrrolo[2,3-b]pyridine;1H-PYRROLO[2,3-B]PYRIDIN-5-OL;5-HYDROXY-7-AZAINDOLE;1H-Pyrrolo[2,3-b]pyridin-5-ol(6CI,9CI);1H-Pyrrolo[2,3-b]pyridin-5-ol90929-73-0;5-HYDROXY-1H-PYRROLO[2,3-B]PYRIDINE;H-PYRROLO[2,3-B]PYRIDIN-5-OL
CAS:98549-88-3
MF:C7H6N2O
MW:134.14
EINECS:802-177-7
Product Categories:PYRIDINE
Mol File:98549-88-3.mol
1H-PYRROLO[2,3-B]PYRIDIN-5-OL Structure
1H-PYRROLO[2,3-B]PYRIDIN-5-OL Chemical Properties
Melting point 219-220°C
Boiling point 381.8±42.0 °C(Predicted)
density 1.41±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Powder
pka6.93±0.20(Predicted)
InChIKeyVUQZKLXKFUBWRP-UHFFFAOYSA-N
Safety Information
Hazard Codes Xi,Xn
Risk Statements 22
Safety Statements 24/25
WGK Germany 3
HazardClass IRRITANT
HS Code 29339900
MSDS Information
1H-PYRROLO[2,3-B]PYRIDIN-5-OL Usage And Synthesis
Chemical PropertiesLight yellow solid
Uses1H-?Pyrrolo[2,?3-?b]?pyridin-?5-?ol is a reagent used in the synthesis of potent VEGFR-2 inhibitors. 7-Azaindole derivative identified as an intermediate in the synthesis of Venetoclax (A112430), a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets.
1H-PYRROLO[2,3-B]PYRIDIN-5-OL Preparation Products And Raw materials
Preparation ProductsMethyl 2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]-4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl]methyl]piperazin-1-yl]benzoate-->5-Benzyloxy-1H-pyrrolo[2,3-b]pyridine
4-CHLORO-5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE 5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE 3-IODO-5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE 1H-Pyrrolo[2,3-b]pyridin-3-ol, 1-(phenylsulfonyl)-, 3-formate 1H-Pyrrolo[2,3-b]pyridin-5-ol, 4-chloro-1-[tris(1-methylethyl)silyl]- 5-METHOXY-6-METHYL-7-AZAINDOLE 1H-PYRROLO[2,3-B]PYRIDIN-5-OL 5-TRIFLUOROMETHOXY-1H-PYRROLO[2,3-B]PYRIDINE 1H-Pyrrolo[2,3-b]pyridin-5-ol, 4-fluoro-1-[tris(1-methylethyl)silyl]- 4-CHLORO-1H-PYRROLO[2,3-B]PYRIDIN-5-OL 5-CHLORO-1H-PYRROLO[2,3-B]PYRIDIN-4-OL 5-METHOXY-PYRROLO[2,3-B]PYRIDINE-1-CARBOXYLICACIDTERT-BUTYLESTER 3-(4-CHLORO-2-METHOXYPHENYL)-1,5-DIMETHYL-1H-PYRROLO[3,2-B]PYRIDIN-7-OL 1H-Pyrrolo[2,3-b]pyridine, 5-methoxy-2-methyl- 1H-Pyrrolo[2,3-b]pyridin-5-ol,1-methyl-,1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-methyl- (9CI) 1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]- 1H-PYRROLO[2,3-B]PYRIDIN-4-OL 5-HYDROXY-6-METHYL-7-AZAINDOLE
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