Benzyl salicylate

Benzyl salicylate Basic information
Product Name:Benzyl salicylate
Synonyms:2-hydroxy-benzoicaciphenylmethylester;Benzoicacid,2-hydroxy-,phenylmethylester;benzyle salicylate;benzylhydroxybenzoate;Salicyclic acid benzyl ester;SALICILATO DE BENCILO;BENZYL SALICYLATE 98+% FCC;SALICYLIC ACID BENZYL ESTER, SECONDARY STANDARD
CAS:118-58-1
MF:C14H12O3
MW:228.24
EINECS:204-262-9
Product Categories:Used in variety of cosmetic and soap essences.;Pharmaceutical Intermediates
Mol File:118-58-1.mol
Benzyl salicylate Structure
Benzyl salicylate Chemical Properties
Melting point 18-20 °C
Boiling point 168-170 °C5 mm Hg(lit.)
density 1.176 g/mL at 25 °C(lit.)
vapor pressure 0.01Pa at 25℃
refractive index n20/D 1.581(lit.)
FEMA 2151 | BENZYL SALICYLATE
Fp >230 °F
storage temp. -20°C
solubility Chloroform (Slightly), Methanol (Slightly)
form neat
pka8.11±0.30(Predicted)
color Thick colorless liquid
Odorpleasant odor
Odor Typebalsamic
Water Solubility Slightly soluble
Merck 14,1144
JECFA Number904
BRN 2115365
InChIKeyZCTQGTTXIYCGGC-UHFFFAOYSA-N
LogP4
CAS DataBase Reference118-58-1(CAS DataBase Reference)
NIST Chemistry ReferenceBenzoic acid, 2-hydroxy-, phenylmethyl ester(118-58-1)
EPA Substance Registry SystemBenzyl salicylate (118-58-1)
Safety Information
Hazard Codes Xi,N
Risk Statements 36/37/38-51/53-43
Safety Statements 26-36-24/25-61-37-24
WGK Germany 2
RTECS VO1750000
TSCA Yes
HS Code 29182900
Hazardous Substances Data118-58-1(Hazardous Substances Data)
ToxicityLD50 orl-rat: 2227 mg/kg FCTXAV 11,1029,73
MSDS Information
ProviderLanguage
Salicylic acid benzyl ester English
ACROS English
SigmaAldrich English
ALFA English
Benzyl salicylate Usage And Synthesis
DescriptionBenzyl salicylate is a salicylic acid benzyl ester, a chemical compound most frequently used in cosmetics. It appears as an almost colorless liquid with a mild odor described as "very faint, sweetfloral, slightly balsamic" by those who can smell it, but many people either can't smell it at all or describe its smell as "musky". Trace impurities can have a significant influence on the odour.[1] It occurs naturally in a variety of plants and plant extracts and is widely used in blends of fragrance materials.
There is some evidence that people can become sensitized to this material and as a result there is a restriction standard concerning the use of this material in fragrances by the International Fragrance Association.
It is used as a solvent for crystalline synthetic musks and as a component and fixative in floral perfumes such as carnation, jasmine, lilac, and wallflower.

Chemical PropertiesBenzyl salicylate has a faint, sweet, floral odor and a sweet, currant-like taste.
Chemical PropertiesBenzyl Salicylate occurs in several essential oils, is a colorless, viscous liquid with a weak, sweet, slightly balsamic odor.
Chemical PropertiesCLEAR SLIGHTLY PINKISH LIQUID
OccurrenceIt has been reported in small amounts in carnation oil (Dianthus caryophyllus L.) and in larger amounts in the oil of Primula auricula. Also found in American cranberry, clove bud, peppermint oil and buckwheat.
Usesbenzyl salicylate is a fragrance found naturally occurring in carnations and in certain members of the primrose family. Although it can be derived for cosmetic use from natural essential oils, such as jasmine oil, neroli, and ylang-ylang, it can also be synthetically manufactured.
UsesBenzyl Salicylate is an chemical compound commonly used in the cosmetic industry. Benzyl Salicylate is also found in essential oils from green tea and was shown to exhibit antioxidant and antimicrobia l activity.
UsesAs fixer in perfumery; in sunscreen preparations.
PreparationBy esterification of salicylic acid with benzyl alcohol.
DefinitionChEBI: Benzyl salicylate is a benzoate ester and a member of phenols. It is functionally related to a salicylic acid.
General DescriptionColorless liquid. Melting point near room temperature (18-20°C).
Air & Water ReactionsSlightly water soluble .
Reactivity ProfileBenzyl salicylate may hydrolyze in aqueous acid or basic solutions. Benzyl salicylate can react with oxidizing materials.
Fire HazardFlash point data for Benzyl salicylate are not available, but Benzyl salicylate is probably combustible.
Flammability and ExplosibilityNonflammable
Contact allergensBenzyl salicylate is used as fixer in perfumery and sunscreen preparations. As a (weak) perfume sensitizer, it has to be listed by name in cosmetic preparations in the EU.
Safety ProfileModerately toxic by ingestion. Seealso BENZYL ALCOHOL, SALICYLIC ACID, andESTERS. Combustible when exposed to heat or flame.When heated to decomposition it emits acrid smoke andirritating fumes. Incompatible with oxidizing materials.
SafetyBenzyl salicylate poses dangers to sensitive skin.  Even in very small amounts, it may cause allergic reactions when applied to the skin. Benzyl salicylate can cause contact dermatitis (skin irritation) to people with sensitive skin types. It is also on the European Commission's list of 26 known allergens. Some of the other ingredients on the fragrance allergen list include linalool, coumarin, geraniol, and limonene.
Salicylic acid Methyl salicylate Phenyl salicylate Tris(trimethylsilyl)phosphate Benzyl alcohol Hexyl salicylate Benzyl methacrylate BUTYL OLEATE 4-Nitrobenzyl chloroformate Benzyl formate Benzyl chloroformate Benzyl Benzyl acetate Methyl acrylate Isoamyl o-hydroxybenzoate Benzyl benzoate Dimethyl succinate Benzyl nicotinate

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