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| | Homophthalic acid Basic information |
| | Homophthalic acid Chemical Properties |
| Melting point | 178-182 °C (lit.) | | Boiling point | 389.5±17.0 °C(Predicted) | | density | 1.392±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | soluble in Dimethylformamide | | pka | 3.72±0.36(Predicted) | | form | Powder | | color | Off-white to light yellow or pale green | | Water Solubility | 12 g/L (20 ºC) | | BRN | 1872069 | | InChIKey | ZHQLTKAVLJKSKR-UHFFFAOYSA-N | | CAS DataBase Reference | 89-51-0(CAS DataBase Reference) | | EPA Substance Registry System | Benzeneacetic acid, 2-carboxy- (89-51-0) |
| | Homophthalic acid Usage And Synthesis |
| Chemical Properties | off-white to light yellow or pale green powder | | Uses | antidepressant | | Uses | A remainder phthalic acid. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 58, p. 4745, 1993 DOI: 10.1021/jo00069a047 | | Purification Methods | Crystallise the acid from boiling H2O (25mL/g; 63mL/g at 20o), aqueous AcOH (m 180o) Dry it at 100o. The S-benzylisothiuronium salt has m 155-156o (from EtOH). [Price Org Synth 22 611942, Grummitt et al. Org Synth Coll Vol III 449 1955, Beilstein 9 H 857, 9 II 617, 9 III 4266, 9 IV 3343.] The anhydride [703-59-3] M 162.1 has m 141-142o. [Beilstein 17/11 V 270.] |
| | Homophthalic acid Preparation Products And Raw materials |
| Raw materials | Indene-->cis-1,2,3,4-tetrahydronaphthalene-2,3-diol-->1,2-Phenylenediacetic acid | | Preparation Products | 1,3-Dichloroisoquinoline-->2-(CYANOMETHYL)BENZOIC ACID-->1,2,3,4-Tetrahydroisoquinoline-1,3-dione-->5-BROMO-HOMOPHTHALIC ACID-->2-(Benzyloxy)-4-phenethylisoquinoline-1,3(2H,4H)-dione-->2-(4-methoxybenzyl)isoquinoline-1,3(2H,4H)-dione-->2-(benzyloxy)isoquinoline-1,3(2H,4H)-dione |
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