PHENYLGLYOXAL MONOHYDRATE

PHENYLGLYOXAL MONOHYDRATE Basic information
Product Name:PHENYLGLYOXAL MONOHYDRATE
Synonyms:BENZOYLFORMALDEHYDE MONOHYDRATE;2,2-DIHYDROXY-1-PHENYL-ETHANONE;PHENYLGLYOXAL;PHENYLGLYOXAL HYDRATE;PHENYLGLYOXAL MONOHYDRATE;P-PHENYLGLYOXAL MONOHYDRATE;2,2-dihydroxy-1-phenyl-ethanon;2,2-dihydroxy-acetophenon
CAS:1075-06-5
MF:C8H8O3
MW:152.15
EINECS:626-958-5
Product Categories:
Mol File:1075-06-5.mol
PHENYLGLYOXAL MONOHYDRATE Structure
PHENYLGLYOXAL MONOHYDRATE Chemical Properties
Melting point 76-79 °C(lit.)
Boiling point 142 °C125 mm Hg(lit.)
density 1.1603 (rough estimate)
refractive index 1.5120 (estimate)
Fp 142°C/125mm
storage temp. Sealed in dry,Room Temperature
solubility 95% ethanol: soluble5%, clear to very slightly hazy, colorless to light yellow
pka10.97±0.41(Predicted)
form Powder
color White to light yellow or pinkish
Water Solubility Partly miscible with water.
BRN 1854721
CAS DataBase Reference1075-06-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 22-26-36
WGK Germany 3
RTECS MD3260000
HS Code 2914.40.4000
Toxicitymouse,LD50,oral,500mg/kg (500mg/kg),Journal of Medicinal and Pharmaceutical Chemistry. Vol. 1, Pg. 365, 1959.
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
PHENYLGLYOXAL MONOHYDRATE Usage And Synthesis
UsesPhenylglyoxal monohydrate was used to modify pig muscle carbonic anhydraseIII and as a specific reagent for arginine groups. It was also used to prepare pyrrolinone and furan derivatives and as as a chemiluminescent reagent for the determination of purines.
Biochem/physiol ActionsPhenylglyoxal is a potent inhibitor of mitochondrial aldehyde dehydrogenase. It reacts with arginine residues in purified Hageman factor (HF, Factor XII) and causes inhibition of its coagulant properties.
PHENYLGLYOXAL MONOHYDRATE Preparation Products And Raw materials
Preparation Products5-PHENYL-1H-1,2,3-TRIAZOLE-->mandelate-->N-(1-hydroxy-2-oxo-2-phenylethyl)acetamide
2,2-Dimethoxy-2-phenylacetophenone Benzoylformic acid Ninhydrin hydrate 2,2-DIHYDROXY-(1H)-BENZ[F]INDENE-1,3(2H)-DIONE MONOHYDRATE sodium phenylglyoxylate 5-Nitroisatin 4-O-(Carboxymethyl)rifamycin DIETHOXYPHENYLACETOPHENONE 2,2-DIHYDROXY-5-METHOXY-1,3-INDANDIONE HYDRATE 2-CHLORO-3' 4'-DIMETHOXYBENZIL 97 4-HYDROXYBENZIL Rifamycin Sodium α,α-Diethoxyacetophenone, Phenylglyoxal 2-diethyl acetal,PHENYLGLYOXAL DIETHYL ACETAL,PHENYLGLYOXAL 2-DIETHYL ACETAL 2,2'-DI(SEC-BUTOXY)ACETOPHENONE 1-(MORPHOLIN-4-YLMETHYL)-1H-INDOLE-2,3-DIONE 4,4'-DIMETHOXYBENZIL 4-NITROPHENYLGLYOXYLIC ACID (2,3-DIOXO-2,3-DIHYDRO-INDOL-1-YL)-ACETIC ACID

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