4-(4-AMINOPHENYL)MORPHOLIN-3-ONE

4-(4-AMINOPHENYL)MORPHOLIN-3-ONE Basic information
Product Name:4-(4-AMINOPHENYL)MORPHOLIN-3-ONE
Synonyms:Rivaroxaban Intermediate 1;Rivaroxaban InterMediate;4-(4-aMinophenyl) Morpholinone;3-Morpholinone, 4-(4-aminophenyl)-;4-(4-Aminophenyl)morpholin-3-one ,97%;4-(4-AMinophenyl)-3-Morpholinone;4-(3-Oxo-4-Morpholinyl)aniline;4-(3-Oxo-4-Morpholinyl)aniline-d4
CAS:438056-69-0
MF:C10H12N2O2
MW:192.21
EINECS:610-147-8
Product Categories:Amines and Anilines;Heterocycles;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Intermediates;Intermediate of Rivaroxaban
Mol File:438056-69-0.mol
4-(4-AMINOPHENYL)MORPHOLIN-3-ONE Structure
4-(4-AMINOPHENYL)MORPHOLIN-3-ONE Chemical Properties
Melting point 171.0 to 175.0 °C
Boiling point 502.3±45.0 °C(Predicted)
density 1.268
vapor pressure 0Pa at 25℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
pka4.85±0.10(Predicted)
color White to Light Brown
Water Solubility 16.6g/L at 20℃
InChIKeyMHCRLDZZHOVFEE-UHFFFAOYSA-N
LogP-0.8 at 25℃
CAS DataBase Reference438056-69-0
Safety Information
Safety Statements 24/25
HazardClass IRRITANT
HS Code 29349990
MSDS Information
4-(4-AMINOPHENYL)MORPHOLIN-3-ONE Usage And Synthesis
Chemical Properties4-(4-AMINOPHENYL)MORPHOLIN-3-ONE is Off-White Solid
Uses4-(4-AMINOPHENYL)MORPHOLIN-3-ONE is used in the preparation of various Morpholine based pharmaceuticals.
UsesRivaroxaban intermediate
Flammability and ExplosibilityNonflammable
1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- m-(Trifluoromethyl)phenylacetic acid 5-CHLOROTHIOPHENE-2-CARBOXYLIC ACID 3-MORPHOLINONE, 4-[4-[(5S)-5-(AMINOMETHYL)-2-OXO-3-OXAZOLIDINYL]PHENYL]- Ethyl (R)-(-)-4-cyano-3-hydroxybutyate 5-CHLOROTHIOPHENE-2-CARBONYL CHLORIDE (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one.HCl 4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one (S)-(+)-GLYCIDYL PHTHALIMIDE 4-(4-NITROPHENYL)MORPHOLIN-3-ONE (S)-(+)-Epichlorohydrin 1,2-Cyclohexanedione POLYSTYRENE IODOSOACETATE Rivaroxaban 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- morpholin-3-one 3-Morpholinone, 4-phenyl- 4-(4-AMINOPHENYL)MORPHOLIN-3-ONE

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