TRIMETHYL-BETA-CYCLODEXTRIN

TRIMETHYL-BETA-CYCLODEXTRIN Basic information
Product Name:TRIMETHYL-BETA-CYCLODEXTRIN
Synonyms:2,3,6-Tri-O-methyl-β-cyclodextrin, Trimethyl-β-cyclodextrin;Permethyl-β-cyclodextrin;Tri-O-methyl-β-cyclodextrin;β-Cyclodextrin permethyl ether;Per-O-methyl-beta-cyclodextrin;Me21-beta-CD;Hydrodex beta-PM;Heptakis(2,3,6-trimethyl)-beta-cyclodextrin
CAS:55216-11-0
MF:C63H112O35
MW:1429.54
EINECS:
Product Categories:Cyclodextrins;Functional Materials;Macrocycles for Host-Guest Chemistry
Mol File:55216-11-0.mol
TRIMETHYL-BETA-CYCLODEXTRIN Structure
TRIMETHYL-BETA-CYCLODEXTRIN Chemical Properties
Melting point 170-178 °C(lit.)
refractive index 160 ° (C=1, CHCl3)
storage temp. 2-8°C
solubility H2O: 50 mg/mL, slightly turbid, colorless
form Solid powder or crystals
color White to off-white
optical activity[α]25/D +157±4°, c = 1% in H2O
BRN 78748
Safety Information
Safety Statements 22-24/25
WGK Germany 3
HS Code 29400090
MSDS Information
ProviderLanguage
SigmaAldrich English
TRIMETHYL-BETA-CYCLODEXTRIN Usage And Synthesis
UsesTrimethyl-β-cyclodextrin (CAS# 55216-11-0) is β-cyclodextrin (C987830) derivative used to solubilize steroids in aqueous solution to increase their bioavailability.
UsesHeptakis(2,3,6-tri-O-methyl)-β-cyclodextrin may be used:
  • To investigate the crystal structure of its complexes with m-iodophenol, 4-biphenylacetic acid and (R)- and (S)-flurbiprofen by X-ray analysis.
  • To study the candidature of its complex with vitamin A for potential application as a drug delivery system for ophthalmic applications by high sensitivity fluorescence spectrometry and high pressure liquid chromatography (HPLC).
  • In the determination of analyte composition in commercial samples by HPLC coupled to mass spectrometry (MS).

UsesHeptakis(2,3,6-tri-O-methyl)-β-cyclodextrin may be used:
  • To investigate the crystal structure of its complexes with m-iodophenol, 4-biphenylacetic acid and (R)- and (S)-flurbiprofen by X-ray analysis.
  • To study the candidature of its complex with vitamin A for potential application as a drug delivery system for ophthalmic applications by high sensitivity fluorescence spectrometry and high pressure liquid chromatography (HPLC) techniques.
  • In the determination of the analyte composition in commercial samples by HPLC coupled to mass spectrometry (MS).

General DescriptionHeptakis(2,3,6-tri-O-methyl)-β-cyclodextrin is a β-cyclodextrin derivative that finds potential use in pharmaceutical, food and cosmetic applications. Its attractive features include: the non-polar cavity desirable for its use as a molecular host for a wide range of molecules and its affinity for organic compounds in solution as well as crystalline phases.
TRIMETHYL-BETA-CYCLODEXTRIN Preparation Products And Raw materials
Cyclohexapentylose 2,6-DI-O-METHYL-BETA-CYCLODEXTRIN Betadex Sulfobutyl Ether Sodium beta-Cyclodextrin methyl ethers 2-Hydroxypropyl-β-cyclodextrin HEPTAKIS-(2 3 6-TRI-O-ETHYL)-BETA- HEPTAKIS(2,3,6-TRI-O-''OCTYL)-BETA-CYCLODEXTRIN HEPTAKIS-(3-O-TRIFLUOROACETYL-2,6-DI-O-PENTYL)-BETA-CYCLODEXTRIN HEPTAKIS-(3-O-BUTYRYL-2,6-DI-O-PENTYL)-BETA-CYCLODEXTRIN Heptakis-(2,6-di-O-butyl-3-O-acetyl)-beta-Cyclodextrin TRIMETHYL-BETA-CYCLODEXTRIN HEPTAKIS(2,6-DI-O-METHYL-3-O-''PENTYL)-BETA-CYCLODEXTRIN* HEPTAKIS(3-O-ALLYL-2,6-DI-O-METHYL)-BETA-CYCLODEXTRIN Heptakis-(2,6-di-O-pentyl-3-O-acetyl)-beta-Cyclodextrin TRIACETYL-BETA-CYCLODEXTRIN 3-O-TRIFLUOROACETYLPERMETHYL-BETA-CYCLODEXTRINE HEPTAKIS(3-O-ACETYL-2 6-DI-O-METHYL)- BETA-CYCLODEXTRIN

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