2-Fluoroanisole

2-Fluoroanisole Basic information

Product Name:	2-Fluoroanisole
Synonyms:	2-Fluoro-1-methoxybenzene;2-Fluoromethoxybenzene;2-Methoxy-1-fluorobenzene;2-Fluorophenyl methyl ether, 1-Fluoro-2-methoxybenzene;2-Fluoroanisole, 98% 25ML;(2-fluorophenyl)(Methyl)-$l^{3}-oxidanyliuM;2- fluoroether;2-Fluoroanisole, 97+%
CAS:	321-28-8
MF:	C7H7FO
MW:	126.13
EINECS:	206-284-4
Product Categories:	Aromatic Ethers;Benzene series;AnisoleSeries;Fluorobenzene;Anisoles, Alkyloxy Compounds & Phenylacetates;Fluorine Compounds;Other fluorin-contained compounds;Fluorinated benzene series;Aryl Fluorinated Building Blocks;Building Blocks;C2 to C7;C7-C8;Chemical Synthesis;Fluorinated Building Blocks;Ethers;Organic Building Blocks;Oxygen Compounds;Organic Building Blocks;Organic Fluorinated Building Blocks;Other Fluorinated Organic Building Blocks;Oxygen Compounds;Imidazoles ,Homopiperidines;bc0001
Mol File:	321-28-8.mol

2-Fluoroanisole Chemical Properties

Melting point	−39 °C(lit.)
Boiling point	154-155 °C(lit.)
density	1.124 g/mL at 25 °C(lit.)
refractive index	n20/D 1.494(lit.)
Fp	140 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Soluble), Methanol (Sparingly)
form	clear liquid
Specific Gravity	1.124
color	Colorless to Light yellow to Light orange
BRN	1859755
InChIKey	JIXDOBAQOWOUPA-UHFFFAOYSA-N
CAS DataBase Reference	321-28-8(CAS DataBase Reference)
NIST Chemistry Reference	Benzene, 1-fluoro-2-methoxy-(321-28-8)

Safety Information

Hazard Codes	F,Xi
Risk Statements	10-36/37/38
Safety Statements	16-36/37/39-27-26
RIDADR	UN 1993 3/PG 3
WGK Germany	3
Hazard Note	Flammable
HazardClass	3
PackingGroup	III
HS Code	29093090

MSDS Information

Provider	Language
1-Fluoro-2-methoxybenzene	English
SigmaAldrich	English
ACROS	English
ALFA	English

2-Fluoroanisole Usage And Synthesis

Chemical Properties	clear colorless liquid
Uses	2-Fluoroanisole is a useful synthetic intermediate with antifungal activity.
Synthesis Reference(s)	Chemistry Letters, 23, p. 1011, 1994 Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8

2-Fluoroanisole Preparation Products And Raw materials

Raw materials	Fluoroboric acid-->o-Anisidine
Preparation Products	3-FLUORO-DL-TYROSINE-->3-Fluoro-4-methoxybenzoic acid-->3-Fluoro-4-hydroxybenzoic acid-->4-CHLORO-2-FLUOROANISOLE-->Benzonitrile, 2-fluoro-3-methoxy- (9CI)-->3-FLUORO-4-METHOXYPHENYLACETIC ACID-->3-FLUORO-2-METHOXYBENZALDEHYDE-->1-Pentanone, 1-(3-fluoro-4-hydroxyphenyl)--->4,4-difluoro-1-(3-fluoro-4-methoxyphenyl)butane-1,3-dione-->3Fluoro-4methoxyvalerophenone

4-BROMO-2-FLUORO-6-NITROANISOLE Fluorine FENFLURAMINE FMOC-ASP(OTBU)-OPFP 2,3,5,6-TETRAFLUOROANISOLE 4-Fluoroanisole Transfluthrin 2-Fluoroanisole 3-Fluoro-4-methoxybenzaldehyde 4,4'-DIMETHOXYOCTAFLUOROBIPHENYL 2,4-DIFLUORO-1-METHOXYBENZENE PENTAFLUOROPHENOXYACETIC ACID 3-Fluoro-4-methoxyacetophenone 3-FLUORO-4-METHOXYPHENYLACETONITRILE Florfenicol 2-(PENTAFLUOROPHENOXY)ETHYL BROMIDE 4-Bromo-2-fluoroanisole 98%,4-Bromo-2-fluoroanisole98% 5-CHLORO-2-FLUOROANISOLE

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