4-Fluorophenylacetonitrile

4-Fluorophenylacetonitrile Basic information

Product Name:	4-Fluorophenylacetonitrile
Synonyms:	P-FLUOROBENZYL CYANIDE;P-FLUOROPHENYLACETONITRILE;PARA-FLUOROBENZYL CYANIDE;p-Fluorobenzyl nitrile;4-Fluorophenylacetonitrile,4-Fluorobenzyl cyanide;4-Fluorophenylacetonitrile, 99% 25GR;The fluorine benzene acetonitrile;(p-fluorophenyl)-acetonitril
CAS:	459-22-3
MF:	C8H6FN
MW:	135.14
EINECS:	207-286-8
Product Categories:	Aromatic Nitriles;Nitrile;Fluorobenzene
Mol File:	459-22-3.mol

4-Fluorophenylacetonitrile Chemical Properties

Melting point	86°C
Boiling point	119-120 °C/18 mmHg (lit.)
density	1.126 g/mL at 25 °C (lit.)
refractive index	n20/D 1.5002(lit.)
Fp	227 °F
storage temp.	Inert atmosphere,Room Temperature
form	Liquid
color	Clear colorless to light yellow
BRN	1907764
Exposure limits	NIOSH: IDLH 25 mg/m3
InChIKey	JHQBLYITVCBGTO-UHFFFAOYSA-N
CAS DataBase Reference	459-22-3(CAS DataBase Reference)
NIST Chemistry Reference	4-Fluorophenylacetic acid nitrile(459-22-3)
EPA Substance Registry System	Benzeneacetonitrile, 4-fluoro- (459-22-3)

Safety Information

MSDS Information

4-Fluorophenylacetonitrile Usage And Synthesis

Chemical Properties	Clear light yellow liquid
Uses	4-Fluorophenylacetonitrile is used as a reagent in the synthesis of novel Daidzein analogs which exhibit anti-influenza activity in vitro. It is also used as a reagent in the synthesis of benzylbenzo[d]thiazole sulfonamides which exhibit anti-inflammatory activity.
General Description	4-Fluorophenylacetonitrile is starting reagent in the synthesis of 1-Alkyl-N-[2-ethyl-2-(4-fluorophenyl)butyl]piperidine-4-carboxamide derivatives.
Biochem/physiol Actions	4-Fluorophenylacetonitrile undergoes biotransformation to 4-Fluorophenylacetic acid by marine fungi, Aspergillus sydowii Ce19.

4-Fluorophenylacetonitrile Preparation Products And Raw materials

Preparation Products

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